Evidence map›Paper›PMID 35911423›Full record

ArticleFrontiers in medicine2022

Analysis of Optic Nerve in Adults With Amblyopia Using OCTA.

Hui Lu, Tonggang Zhang, Tao Yue, Xiaoqin Li, Bingfen Ma, Hongxia Liu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07417046 (Possible Beneficial Effects Of Combined Fluoxetine And Occlusion Therapy In Improving And Maintaining Vision In Amblyopia Using Optical Coherence Tomography Angiography), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07417046 narecruitingnot on this mapstarted 2024, after this paper: background citation

Possible Beneficial Effects Of Combined Fluoxetine And Occlusion Therapy In Improving And Maintaining Vision In Amblyopia Using Optical Coherence Tomography Angiography (OCTA) And Visual Evoked Potential (VEP)

TypeinterventionalSponsorMinia UniversityRan2024 to 2026Enrolled50ConditionsAmblyopia, VEPArmsFlouxetine, Patching therapy
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hui LuDepartment of Ophthalmology, Zibo Central Hospital, Zibo, China.
Tonggang ZhangDepartment of Medical Device, Zibo Central Hospital, Zibo, China.
Tao YueDepartment of Gerontology, Zibo Central Hospital, Zibo, China.
Xiaoqin LiDepartment of Ophthalmology, Zibo Central Hospital, Zibo, China.
Bingfen MaDepartment of Ophthalmology, Zibo Central Hospital, Zibo, China.
Hongxia LiuDepartment of Ophthalmology, Zibo Central Hospital, Zibo, China.
Central Hospital of Zibo · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim was to quantify and compare papillary and peripapillary vessel density in amblyopic eyes of adults and age-matched controls. Methods: This cross-sectional study involved 20 eyes from 10 subjects with anisometropic amblyopia and 12 eyes of 6 age- and gender-matched healthy controls. Optical coherence tomography angiography (OCTA) was performed on all participants. SPSS 20 was used for data analysis. Results: The mean subject age was 35.7 ± 10.04 years (range 18-47) in the amblyopia group and 34.67 ± 6.92 years (range 23-42) in the control group. The diopter of amblyopia ranges from +3 to +5 ds. The mean inside optic disk capillary vessel density (CVD) was 41.88 ± 6.55% in amblyopic eyes, 49.23 ± 6.55% in fellow eyes, and 50.23 ± 4% in control eyes ( Conclusion: Our present study revealed lower vessel density inside the optic disc of adult patients with anisometropic amblyopia. However, further studies are really needed to determine the clinical relevance of this finding.

Indexed as

adultsamblyopiahyperopiaoptical coherence tomography angiographyperipapillary microvasculature

Identifiers

PMID35911423
PMCPMC9330213
OpenAlexW4285387119

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.