Evidence map›Paper›PMID 35911409›Full record

SynthesisFrontiers in medicine2022

A systematic review of multidomain and lifestyle interventions to support the intrinsic capacity of the older population.

Roberta Bevilacqua, Luca Soraci, Vera Stara, Giovanni Renato Riccardi, Andrea Corsonello, Giuseppe Pelliccioni, Fabrizia Lattanzio, Sara Casaccia, Johanna Möller, Rainer Wieching and 6 more

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06753643 (Implementing the National Frailty Policy in Singapore's Primary Care), which is not on this map. Cited by 35 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06753643 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Implementing the National Frailty Policy in Singapore's Primary Care: A Pilot Feasibility Study of The Intrinsic Capacity ProMotion in PrimAry Care for The Frail Program (IMPACTFrail)

TypeobservationalSponsorGeriatric Education and Research InstituteRan2025 to 2026Enrolled180ConditionsHealthy Ageing, FrailtyArmsThe IMPACTFrail programme
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  7. Relative impact of multidomain lifestyle interventions on deficit accumulation frailty over 24 months in the U.S. POINTER trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
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  10. Associations Between Deficit Accumulation Frailty and Baseline Markers of Lifestyle in the U.S. POINTER Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Roberta BevilacquaScientific Direction, IRCCS INRCA, Ancona, Italy.
Luca SoraciUnit of Geriatric Medicine, IRCCS INRCA, Cosenza, Italy.
Vera StaraScientific Direction, IRCCS INRCA, Ancona, Italy.
Giovanni Renato RiccardiClinical Unit of Physical Rehabilitation, IRCCS INRCA, Ancona, Italy.
Andrea CorsonelloUnit of Geriatric Medicine, IRCCS INRCA, Cosenza, Italy.
Giuseppe PelliccioniUnit of Neurology, IRCCS INRCA, Ancona, Italy.
Fabrizia LattanzioScientific Direction, IRCCS INRCA, Ancona, Italy.
Sara CasacciaDepartment of Industrial Engineering and Mathematical Sciences, Polytechnic University of Marche, Ancona, Italy.
Johanna MöllerDepartment Elderly Care, Diocesan Caritas Association for the Archdiocese of Cologne, Cologne, Germany.
Rainer WiechingUniversität Siegen, Wirtschaftsinformatik und Neue Medien, Siegen, Germany.
Toshimi OgawaSmart-Aging Research Center, Tohoku University, Sendai, Japan.
Suichiro WatanabeSmart-Aging Research Center, Tohoku University, Sendai, Japan.
Keisuke KokobunSmart-Aging Research Center, Tohoku University, Sendai, Japan.
Izumi KondoDepartment of Rehabilitation Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.
Eiko TakanoDepartment of Rehabilitation Medicine, National Center for Geriatrics and Gerontology, Obu, Japan.
Elvira MaranesiScientific Direction, IRCCS INRCA, Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The focus on intrinsic capacity (IC) could help clinicians to design interventions to improve the health of the older population. This review aims to map the current state of the art in the field of multi-domain interventions based on the IC framework, to allow health professionals in identifying personalized clinical interventions, oriented to empower the older people with a holistic and positive approach. Methods: A systematic review of the literature was conducted in July 2021 analyzing manuscripts and articles of the last 10.5 years from PubMed, Scopus, Embase, Google Scholar and Elsevier databases. A total of 12 papers were included. Results: The majority of successful interventions are based on a goal setting approach where the older people are involved in the definition of the strategy to follow to remain active and independent. None of the study have used the IC as a framework to design a clinical intervention. Conclusion: To the best of our knowledge, no other reviews are reported in the literature regarding the IC. Our study offers several research directions, which may take the existing debates to the next level.

Indexed as

active and healthy agingcognitive supportfunctional abilitygeriatricsintrinsic capacitymulticomponent interventionmultidomainpsychological support

Identifiers

PMID35911409
PMCPMC9335156

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.