Evidence map›Paper›PMID 35911407›Full record

ArticleFrontiers in medicine2022

The Digital Twin in Medicine: A Key to the Future of Healthcare?

Tianze Sun, Xiwang He, Xueguan Song, Liming Shu, Zhonghai Li

Abstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
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  5. Review
  6. Article
  7. A Real-Time Digital Twin for Human Cardiovascular Applications.International journal for numerical methods in biomedical engineering · 2026
    Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Digital Twin Technology In Radiology.Journal of imaging informatics in medicine · 2026
    Review
  14. Advances in 3D Printing for Removable Prosthetics-Insights and Perspectives.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
    Review
  15. Article
  16. Article
  17. Article
  18. Decrypting network physiology for clinical practice.Frontiers in network physiology · 2026
    Review
  19. Review
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tianze SunDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xiwang HeSchool of Mechanical Engineering, Dalian University of Technology, Dalian, China.
Xueguan SongSchool of Mechanical Engineering, Dalian University of Technology, Dalian, China.
Liming ShuResearch Into Artifacts, Center for Engineering, School of Engineering, The University of Tokyo, Bunkyo, Japan.
Zhonghai LiDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a growing need for precise diagnosis and personalized treatment of disease in recent years. Providing treatment tailored to each patient and maximizing efficacy and efficiency are broad goals of the healthcare system. As an engineering concept that connects the physical entity and digital space, the digital twin (DT) entered our lives at the beginning of Industry 4.0. It is evaluated as a revolution in many industrial fields and has shown the potential to be widely used in the field of medicine. This technology can offer innovative solutions for precise diagnosis and personalized treatment processes. Although there are difficulties in data collection, data fusion, and accurate simulation at this stage, we speculated that the DT may have an increasing use in the future and will become a new platform for personal health management and healthcare services. We introduced the DT technology and discussed the advantages and limitations of its applications in the medical field. This article aims to provide a perspective that combining Big Data, the Internet of Things (IoT), and artificial intelligence (AI) technology; the DT will help establish high-resolution models of patients to achieve precise diagnosis and personalized treatment.

Indexed as

artificial intelligence (AI)big datadigital twin (DT)healthcareprecision medicine

Identifiers

PMID35911407
PMCPMC9330225

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.