Evidence map›Paper›PMID 35911172›Full record

ArticleJournal of bio- and tribo-corrosion2022

Microstructure and electrochemical behavior of contemporary Ti6Al4V implant alloys.

Mozart Queiroz Neto, Simona Radice, Deborah J Hall, Nicholas B Frisch, Mathew T Mathew, Alfons Fischer, Joshua J Jacobs, Robin Pourzal

Abstract read
In one paragraph

Article in Journal of bio- and tribo-corrosion, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mozart Queiroz NetoDepartment of Orthopedic Surgery, Rush University Medical Center, 1611 W, Harrison Street, Suite 201, Chicago, IL-60612, USA.
Simona RadiceDepartment of Orthopedic Surgery, Rush University Medical Center, 1611 W, Harrison Street, Suite 201, Chicago, IL-60612, USA.
Deborah J HallDepartment of Orthopedic Surgery, Rush University Medical Center, 1611 W, Harrison Street, Suite 201, Chicago, IL-60612, USA.
Nicholas B FrischAscension Providence Rochester Hospital, 1135 West University Dr, Suite 450, Rochester, MI- 48307, USA.
Mathew T MathewDepartment of Biomedical Science, University of Illinois College of Medicine, Rockford, IL, 61107, USA.
Alfons FischerDepartment of Orthopedic Surgery, Rush University Medical Center, 1611 W, Harrison Street, Suite 201, Chicago, IL-60612, USA.
Joshua J JacobsDepartment of Orthopedic Surgery, Rush University Medical Center, 1611 W, Harrison Street, Suite 201, Chicago, IL-60612, USA.
Robin PourzalDepartment of Orthopedic Surgery, Rush University Medical Center, 1611 W, Harrison Street, Suite 201, Chicago, IL-60612, USA.

Funding

Corrosion Induced Hip Implant Failure: Synergistic Interactions of Patient, Material, Design, and Surgical FactorsR01AR070181 · NIAMS · RUSH UNIVERSITY MEDICAL CENTER · PI LUNDBERG, HANNAH JEAN, MATHEW, MATHEW THOPPIL · 2016 to 2020
$2.3M
NIAMS NIH HHS R01 AR070181
6 · The paper itself

Abstract

Ti6Al4V is the most common titanium alloy within the biomaterial field. While material standards for different variations of this alloy exist, there are only minimal requirements with respect to its microstructure which is directly related to the alloy's properties. Thus, a better understanding of the Ti6Al4V microstructure of common contemporary implant components and its effect on the electrochemical behavior is needed; including additively manufactured (AM) devices. Therefore, this study aimed at characterizing the microstructures of conventional and AM total joint replacement components, and to identify the effect of microstructure on the electrochemical behavior. Thus, 22 components from conventional (surgically retrieved cast and wrought implants) and AM implants (not previously implanted) were analysed to characterize microstructure by means of electron backscatter diffraction (EBSD) and energy dispersive X-Ray spectroscopy (EDS), and tested to determine its electrochemical behavior (potentiodynamic polarization and EIS). The microstructure of the conventional implants varied broadly but could be categorized into four groups as to their grain size and shape: fine equiaxed, coarse equiaxed, bimodal, and lamellar. The AM components exhibited a fifth category: lath-type. The AM components had a network of β-phase along the α-phase grain boundaries, prior β-grains, and manufacturing voids. Finally, the electrochemical study showed that the equiaxed coarse grains and lath-type grains (AM components) had inferior electrochemical behavior, whereas cast alloys had superior electrochemical behaviour; fine-grained wrought alloys likely provide the best compromise between electrochemical and mechanical properties.

Indexed as

additive manufacturingcorrosion behaviorimplant alloy microstructureTi6Al4Vtotal joint replacements

Identifiers

PMID35911172
PMCPMC9328449

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.