Evidence map›Paper›PMID 35911136›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

High CHAF1A Expression Levels Are Positively-Correlated with PD-L1 Expression and Indicate Poor Prognosis in Gastric Cancer.

Zhehan Bao, Yanqiang Zhang, Pengcheng Yu, Yi Wang, Can Hu, Yuhang Xia, Li Yuan, Zhiyuan Xu, Xiangdong Cheng

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhehan BaoThe First Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0001-7080-5945
Yanqiang ZhangThe Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou 310022, China.ORCID https://orcid.org/0000-0002-9118-9800
Pengcheng YuThe First Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0003-4131-9811
Yi WangThe First Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0002-5714-5943
Can HuThe First Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0002-8687-8310
Yuhang XiaThe First Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou 310053, China.ORCID https://orcid.org/0000-0001-6714-0268
Li YuanThe Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou 310022, China.ORCID https://orcid.org/0000-0002-6245-9437
Zhiyuan XuThe Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou 310022, China.ORCID https://orcid.org/0000-0002-7257-6856
Xiangdong ChengThe Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institutes of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou 310022, China.ORCID https://orcid.org/0000-0003-1470-2831
Zhejiang Chinese Medical University · CNZhejiang Cancer Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to analyze the association between the expression of chromatin assembly factor 1 subunit A (CHAF1A) in gastric cancer (GC) and clinicopathological features, disease prognosis, and expression of programmed cell death-ligand 1 (PD-L1). Results: A significantly higher level of CHAF1A expression in GC tissues was found compared to that in paracancerous tissues ( Conclusion: High CHAF1A expression is associated with poor GC prognosis and positively correlated to PD-L1 expression. Thus, CHAF1A expression level may be used as a novel biomarker for GC diagnosis.

Identifiers

PMID35911136
PMCPMC9325625
OpenAlexW4286213417

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.