Evidence map›Paper›PMID 35910763›Full record

ReviewPeerJ2022

The immunomodulatory potential of phage therapy to treat acne: a review on bacterial lysis and immunomodulation.

Juan Farfán, John M Gonzalez, Martha Vives

Open access · goldAbstract readReview
In one paragraph

Review in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Multidrug-resistantFrontiers in microbiology · 2025
    Review
  6. Article
  7. Antibacterial activity and impact on keratinocyte cell growth ofCurrent research in microbial sciences · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Juan FarfánBiological Sciences Department, Faculty of Science, Universidad de Los Andes, Bogotá, Bogotá D.C., Colombia.
John M GonzalezSchool of Medicine, Universidad de Los Andes, Bogotá, Bogotá D.C., Colombia.
Martha VivesBiological Sciences Department, Faculty of Science, Universidad de Los Andes, Bogotá, Bogotá D.C., Colombia.
Universidad de Los Andes · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Characterized by an inflammatory pathogenesis, acne is the most common skin disorder worldwide. Altered sebum production, abnormal proliferation of keratinocytes, and microbiota dysbiosis represented by disbalance in Methodology: Literature review was performed using four different databases (Europe PubMed Central-ePMC, Google Scholar, PubMed, and ScienceDirect). Articles were ordered and selected according to their year of publication, number of citations, and quartile of the publishing journal. Results: The use of lytic bacteriophages to control bacterial infections has proven its promising results, and anti-inflammatory effects have been found for some bacteriophages and phage therapy. These effects can be related to bacterial elimination or direct interaction with immune cells that result in the regulation of pro-inflammatory cytokines. Studies on Conclusions:

Indexed as

Acne VulgarisBacteriophagesPhage TherapyAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsMiceSkinAnti-Bacterial AgentsAnti-Inflammatory AgentsAcneBacteriophageCutibacterium acnesCutibacterium acnes bacteriophagesImmunomodulationPhage therapyPropionibacterium acnes

Identifiers

PMID35910763
PMCPMC9332329
OpenAlexW4287218145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.