Evidence map›Paper›PMID 35910688›Full record

ArticleInternet interventions2022

Reducing stress and anxiety in patients with myocardial infarction with non-obstructive coronary arteries or Takotsubo syndrome: A non-randomized feasibility study.

Elisabet Rondung, Sophia Monica Humphries, Erik Martin Gustaf Olsson, Runa Sundelin, Fredrika Norlund, Claes Held, Jonas Spaak, Per Tornvall, Patrik Lyngå

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Internet interventions, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Mobile health delivered physical activity after mild stroke or transient ischemic attack: Is it feasible and acceptable?International journal of stroke : official journal of the International Stroke Society · 2025
    Trial
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Elisabet RondungDepartment of Psychology and Social Work, Mid Sweden University, 831 25 Östersund, Sweden.
Sophia Monica HumphriesDepartment of Women's and Children's Health, Uppsala University, 751 85 Uppsala, Sweden.
Erik Martin Gustaf OlssonDepartment of Women's and Children's Health, Uppsala University, 751 85 Uppsala, Sweden.
Runa SundelinDepartment of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Fredrika NorlundDepartment of Women's and Children's Health, Uppsala University, 751 85 Uppsala, Sweden.
Claes HeldDepartment of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, 751 83 Uppsala, Sweden.
Jonas SpaakDepartment of Clinical Sciences, Danderyd University Hospital, Karolinska Institutet, Stockholm, Sweden.
Per TornvallDepartment of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Patrik LyngåDepartment of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Uppsala University · SEKarolinska Institutet · SEStockholm South General Hospital · SEMid Sweden University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: In the aftermath of a myocardial infarction with non-obstructive coronary arteries (MINOCA) or Takotsubo syndrome (TS), patients commonly express high levels of stress and anxiety. Current treatment alternatives rarely address these issues. The planned Methods: Participant recruitment and screening took place before discharge from the coronary care unit at a large Swedish hospital. Eligible patients were invited to a nine-step psychologist guided, internet-based CBT intervention. The sample size was set in advance to 10 participants completing the intervention. The recruitment and flow of participants were documented and evaluated in relation to seven pre-defined progression criteria. Self-reports of anxiety (HADS-A), stress (PSS-14), cardiac anxiety (CAQ), posttraumatic stress (IES-6) and quality of life (Rand-36), collected at screening, pre-intervention and post-intervention, were analysed descriptively and by effect sizes (Cohen's Results: Six out of seven progression criteria yielded no concerns. Out of 49 patients with a working diagnosis of MINOCA or TS, 31 were eligible for screening, 26 consented to participate, and 14 were eligible with regard to symptoms of stress and/or anxiety. Eleven completed the pre-assessment and were given access the intervention, and 9 completed the intervention. Only the number of patients screened prior to eligibility assessment was slightly lower than expected, indicating possible concerns. Self-reports of anxiety, stress, cardiac anxiety, posttraumatic stress, and quality of life all indicated symptom reduction from pre- to post-intervention, generally showing large effect sizes ( Conclusion: Conducting a full scale RCT was found feasible. Inclusion of more study sites and minor amendments to the protocol and intervention were decided to improve feasibility further. Trial registration: Clinicaltrials.govNCT04178434.

Indexed as

AnxietyCognitive behavioral therapyInternet-based interventionMINOCAStressTakotsubo syndrome

Identifiers

PMID35910688
PMCPMC9334337
OpenAlexW4286268175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.