Evidence map›Paper›PMID 35910530›Full record

ArticleJournal of diabetes research2022

Effects of Sodium-Glucose Cotransporter-2 Inhibitors on Urine Albumin to Creatinine Ratio in Type 2 Diabetes Mellitus Patients and Medication Care.

Dong-Dong Wang, Cun Zhang, Yang Yang, Su-Mei He, Ping Zhu, Xiao Chen

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In one paragraph

Article in Journal of diabetes research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dong-Dong WangJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy & School of Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0002-4019-5530
Cun ZhangDepartment of Pharmacy, Xuzhou Oriental Hospital Affiliated to Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0002-6080-7338
Yang YangDepartment of Pharmacy, The Affiliated Changzhou Children's Hospital of Nantong University, Changzhou 213003, China.ORCID https://orcid.org/0000-0002-2549-8699
Su-Mei HeDepartment of Pharmacy, The Affiliated Suzhou Science & Technology Town Hospital of Nanjing Medical University, Suzhou Jiangsu 215153, China.ORCID https://orcid.org/0000-0002-9229-2367
Ping ZhuDepartment of Endocrinology, Huaian Hospital of Huaian City, Huaian, Jiangsu 223200, China.ORCID https://orcid.org/0000-0003-2345-4032
Xiao ChenSchool of Nursing, Xuzhou Medical University, Xuzhou, Jiangsu 221004, China.ORCID https://orcid.org/0000-0002-0386-3675

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The purpose of this study was to explore the effects of sodium-glucose cotransporter-2 (SGLT-2) inhibitors on urine albumin to creatinine ratio (UACR) in type 2 diabetes mellitus (T2DM) patients and to recommend appropriate medication care scheme. Methods: 8371 T2DM patients from four dapagliflozin studies and two canagliflozin studies were collected for analyzing with nonlinear mixed effect model (NONMEM). The change rates of UACR from baseline were intended to be evaluation indicators. Results: In the present study, there was no significant difference in the effects on UACR using dapagliflozin or canagliflozin treatment in T2DM patients. The maximal effect ( Conclusions: To our knowledge, the present study explored the effects of SGLT-2 inhibitors on UACR in T2DM patients, meanwhile, recommended appropriate medication care scheme for the first time.

Indexed as

Diabetes Mellitus, Type 2Sodium-Glucose Transporter 2 InhibitorsAlbuminsCanagliflozinCreatinineGlucoseHumansHypoglycemic AgentsSodiumAlbuminsCanagliflozinCreatinineGlucoseHypoglycemic AgentsSodiumSodium-Glucose Transporter 2 Inhibitors

Identifiers

PMID35910530
PMCPMC9328955

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.