Evidence map›Paper›PMID 35910354›Full record

ArticleFrontiers in pharmacology2022

Effects of 3,4-Methylenedioxymethamphetamine on Conditioned Fear Extinction and Retention in a Crossover Study in Healthy Subjects.

Patrick Vizeli, Isabelle Straumann, Urs Duthaler, Nimmy Varghese, Anne Eckert, Martin P Paulus, Victoria Risbrough, Matthias E Liechti

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Acute effects of MDMA, MDA, lysine-MDMA, and lysine-MDA in a randomized, double-blind, placebo-controlled, crossover trial in healthy participants.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  3. MDMA enhances positive affective responses to social feedback.Journal of psychopharmacology (Oxford, England) · 2024
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  6. MDMA alters fear extinction, and reduces alcohol consumption in inbred alcohol preferring iP rats but not outbred Wistar rats.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Patrick VizeliClinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Isabelle StraumannClinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Urs DuthalerClinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Nimmy VarghesePsychiatric University Hospital, University of Basel, Basel, Switzerland.
Anne EckertPsychiatric University Hospital, University of Basel, Basel, Switzerland.
Martin P PaulusLaureate Institute for Brain Research, Tulsa, OK, United States.
Victoria RisbroughDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, United States.
Matthias E LiechtiClinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
University Hospital of Basel · CHUniversity of Basel · CHLaureate Institute for Brain Research · USUniversity of California, San Diego · US

Funding

Neuronal exosomes to identify biomarkers and pathology of deployment-related TBII01BX004312 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI RISBROUGH, VICTORIA B, RISSMAN, ROBERT · 2019 to 2022
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BLRD VA I01 BX004312
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

fear extinctionfear-potentiated startlehealthy subjectsMDMA and fear extinction paradigmsoxytocinskin conductance response

Identifiers

PMID35910354
PMCPMC9326355
OpenAlexW4285087910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.