Evidence map›Paper›PMID 35910182›Full record

ArticleACS omega2022

Microparticle Manipulation Based on the Bulk Acoustic Wave Combined with the Liquid Crystal Backflow Effect Driving in 2D/3D Platforms.

Yanfang Guan, Xiaoliang Wang, Guangyu Liu, Wujie Li, Kun Zhang, Baoshuo Sun, Feifan Shi, Yanbo Hui, Bingsheng Yan, Jie Xu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yanfang GuanSchool of Electromechanical Engineering, Henan University of Technology, Zhengzhou 450001, China.ORCID https://orcid.org/0000-0001-5615-5077
Xiaoliang WangSchool of Electromechanical Engineering, Henan University of Technology, Zhengzhou 450001, China.
Guangyu LiuSchool of Electromechanical Engineering, Henan University of Technology, Zhengzhou 450001, China.
Wujie LiSchool of Electromechanical Engineering, Henan University of Technology, Zhengzhou 450001, China.
Kun ZhangSchool of Electromechanical Engineering, Henan University of Technology, Zhengzhou 450001, China.
Baoshuo SunSchool of Electromechanical Engineering, Henan University of Technology, Zhengzhou 450001, China.
Feifan ShiSchool of Electromechanical Engineering, Henan University of Technology, Zhengzhou 450001, China.
Yanbo HuiSchool of Electromechanical Engineering, Henan University of Technology, Zhengzhou 450001, China.
Bingsheng YanSchool of Electromechanical Engineering, Henan University of Technology, Zhengzhou 450001, China.
Jie XuMechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States.
Zaihui WuZhengzhou Institute of Biomedical Engineering and Technology, Zhengzhou 450001, China.
Zhiyong DuanNano Opto-mechatronics & Biomedical Engineering Lab, Zhengzhou University, Zhengzhou 450001, China.
Ronghan WeiNano Opto-mechatronics & Biomedical Engineering Lab, Zhengzhou University, Zhengzhou 450001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microparticle manipulation has been widely used in clinical diagnosis, cell separation, and biochemical analysis via optics, electronics, magnetics, or acoustic wave driving. Among them, the bulk acoustic wave (BAW) driving method has been increasingly adopted because of non-contact, easy control, and precise manipulation. However, its low manipulation efficiency limits the usage of the BAW driving in high viscosity solutions. Therefore, in order to obtain larger driving force and more flexible manipulation of microparticles, both two-dimensional (2D) and three-dimensional (3D) platforms based on the BAW and liquid crystal backflow effect (LCBE) driving in liquid crystal (LC) solutions are proposed. The driving forces applied on the microparticles allow for the change of microparticle moving direction, which is also ascertained through theory analysis combined with various driving methods. Specifically, the maximum moving speed (68.78 μm/s) of the polystyrene particles is obtained by the BAW (13 Vpp) combined with LCBE (30 V) at a low frequency of 7.2 kHz in the 2D platform. Precise position manipulation in 3D is also fulfilled through a programmable logic control model using polystyrene particles as a demonstration. In addition, red blood cells mixed with LC solutions are arranged in a line or gathered in the pressure nodes of the BAW forces along with sinusoid signals generated by various transducer combinations. Therefore, it is approved that the LC solution that induces the LCBE force could increase the microparticle manipulation efficiency in both 2D and 3D platforms. The proposed method will open up new avenues in particle manipulation and benefit a variety of applications in cell separation, drug synthesis, analytical chemistry, and others.

Identifiers

PMID35910182
PMCPMC9330138

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.