Evidence map›Paper›PMID 35910084›Full record

ReviewNeuroscience insights2022

The Effectiveness of Perturbation-Based Training in the Treatment of Patients With Stroke: A Systematic Review and Meta-Analysis.

Mohamed Salaheldien Mohamed Alayat, Nahla Ahmad Almatrafi, Amir Abdel Raouf El Fiky, Ahmed Mohamed Elsodany, Tamer Mohamed Shousha, Reem Basuodan

Registry-linked trialAbstract readReview
In one paragraph

Review in Neuroscience insights, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07697794 (Environmental-Perturbation Balance Training Improves Functional Outcomes in Patients With Subacute Stroke), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07697794 nawithdrawnnot on this mapstarted 2026, after this paper: background citation

Environmental-Perturbation Balance Training Improves Functional Outcomes in Patients With Subacute Stroke: A Prospective Randomized Controlled Trial

TypeinterventionalSponsorFirst People's Hospital of ShenyangRan2026 to 2027Enrolled0ConditionsStrokeArmsEnvironmental-perturbation balance training, Conventional rehabilitation training
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Neuromuscular Mechanisms of Motor Adaptation to Repeated Treadmill-Slip Perturbations During Stance in Healthy Young Adults.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohamed Salaheldien Mohamed AlayatPhysiotherapy and Rehabilitation Department, Faculty of Applied Medical Science, Umm Al-Qura University, Makkah, Saudi Arabia.ORCID https://orcid.org/0000-0003-1039-7550
Nahla Ahmad AlmatrafiPhysiotherapy and Rehabilitation Department, Faculty of Applied Medical Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Amir Abdel Raouf El FikyDepartment of Physical Therapy for Neurological Disorders and its Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt.
Ahmed Mohamed ElsodanyDepartment of Basic Science, Faculty of Physical Therapy, Cairo University, Egypt.
Tamer Mohamed ShoushaDepartment of Physiotherapy, College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.
Reem BasuodanDepartment of Rehabilitation Sciences, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the effectiveness of perturbation-based training (PBT) on balance and balance confidence in patients with stroke. Methods: Systematic searching was performed from inception to November 2021. The inclusion criteria were RCTs assessed the effectiveness of PBT in patients with stroke. Data regarding participants, intervention parameters, outcome measures, follow-up, and main results were extracted. The outcomes were balance and balance confidence. Methodological quality and quality of evidence were assessed using the Physiotherapy Evidence Database (PEDro) scale and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system; respectively. Data analysis: A total of 7 articles )271 patients) were included. A meta-analysis using a random-effect model was performed on 6 studies. Standardized mean difference (SMD) with a 95% confidence interval was calculated for balance and balance confidence. Results: PEDro scale revealed 5 good-quality and 2 fair-quality studies. The currently available evidence showed significant effect of PBT in improving balance (SMD 0.60 [95% CI 0.15-1.06]; Conclusion: PBT may improve balance in patients with stroke, however its effect on balance confidence was limited. The quality of the evidence was low or very low with little confidence in the effect estimate, which suggests further high-quality trials are required. Registration: PROSPERO registration number (CRD42021291474).

Indexed as

balanceexercisePerturbationstroketraining

Identifiers

PMID35910084
PMCPMC9329815

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.