Evidence map›Paper›PMID 35909974›Full record

ArticleFrontiers in cellular and infection microbiology2022

Effects of the Sex Steroid Hormone Estradiol on Biofilm Growth of Cystic Fibrosis

Jiwar Al-Zawity, Faria Afzal, Aysha Awan, Daniela Nordhoff, Alexander Kleimann, Daniel Wesner, Tristan Montier, Tony Le Gall, Mareike Müller

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Testosterone Modulates Virulence-Associated Phenotypes ofPathogens (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Antibacterial properties ofFrontiers in nutrition · 2025
    Article
  7. Biofilm · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jiwar Al-ZawityPhysical Chemistry I and Research Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, University of Siegen, Siegen, Germany.
Faria AfzalPhysical Chemistry I and Research Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, University of Siegen, Siegen, Germany.
Aysha AwanPhysical Chemistry I and Research Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, University of Siegen, Siegen, Germany.
Daniela NordhoffPhysical Chemistry I and Research Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, University of Siegen, Siegen, Germany.
Alexander KleimannPhysical Chemistry I and Research Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, University of Siegen, Siegen, Germany.
Daniel WesnerPhysical Chemistry I and Research Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, University of Siegen, Siegen, Germany.
Tristan MontierINSERM, Univ Brest, EFS, UMR 1078, GGB-GTCA, Brest, France.
Tony Le GallINSERM, Univ Brest, EFS, UMR 1078, GGB-GTCA, Brest, France.
Mareike MüllerPhysical Chemistry I and Research Center of Micro- and Nanochemistry and (Bio)Technology (Cμ), Department of Chemistry and Biology, University of Siegen, Siegen, Germany.
University of Siegen · DEFolkwang University of the Arts · DEInserm · FRUniversité de Bretagne Occidentale · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Women with cystic fibrosis (CF) have a significantly lower life expectancy compared to men, which is indicated by an earlier impairment of lung function due to chronic colonization with biofilm formed by

Indexed as

Cystic FibrosisPseudomonas InfectionsBiofilmsEstradiolExtracellular Polymeric Substance MatrixFemaleHumansPseudomonas aeruginosaEstradiolbiofilm growthclinical isolatescystic fibrosisestradiolPseudomonas aeruginosaquorum sensing

Identifiers

PMID35909974
PMCPMC9326073
OpenAlexW4285084763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.