Evidence map›Paper›PMID 35909831›Full record

SynthesisComputational intelligence and neuroscience2022

The Efficacy and Safety of Mizoribine versus Mycophenolate Mofetil for the Treatment of Renal Transplantation: A Systematic Review and Meta-Analysis.

Jie Chen, Hua Liu, Wenjun Yin, Zhengguang Xu, Zekai Chen, Wingkeung Yiu

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Computational intelligence and neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jie ChenUrinary Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Hua LiuUrinarySurgery, Southern Hospital of Southern Medical University, Guangzhou, China.
Wenjun YinUrinary Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Zhengguang XuUrinary Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Zekai ChenUrinary Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Wingkeung YiuUrinary Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.ORCID https://orcid.org/0000-0002-1621-341X
First Affiliated Hospital of Jinan University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mizoribine (MZR) is widely used in Asia due to its high safety and low cost, and comparative studies of its safety and efficacy with the first-line drug mycophenolate mofetil (MMF) have been carried out. This paper aimed to compare the efficacy and safety of MZR and MMF in immunosuppressive therapy of renal transplantation by meta-analysis. Methods: We searched randomized controlled trials (RCTs) comparing MZR versus MMF for renal transplantation in PubMed, Excerpta Medica Database (EMBASE), Cochrane Library, Web of Science, WanFang Database, China National Knowledge Infrastructure (CNKI), and Chinese Biomedical Database (CBM). Articles were assessed for their risk of bias using the Cochrane Collaboration. Forest plots and funnel plots were also performed on the included articles. Results: A total of twelve studies with 1103 patients were selected in the analysis. No significant difference were observed between the MZR group and the MMF group for the rate of acute rejection (RR = 1.50, 95% CI 1.11 to 2.01,

Indexed as

Cytomegalovirus InfectionsGastrointestinal DiseasesHyperuricemiaKidney TransplantationHumansImmunosuppressive AgentsMycophenolic AcidRibonucleosidesImmunosuppressive AgentsmizoribineMycophenolic AcidRibonucleosides

Identifiers

PMID35909831
PMCPMC9337967
OpenAlexW4286615211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.