Evidence map›Paper›PMID 35909570›Full record

ArticleFrontiers in endocrinology2022

Influence of sperm DNA fragmentation on the clinical outcome of

Chunhui Zhu, Fang Chen, Shengmin Zhang, Hong She, Yun Ju, Xidong Wen, Chunxia Yang, Yan Sun, Naijun Dong, Tongmin Xue and 3 more

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  13. Male aging in germ cells: What are we inheriting?Genetics and molecular biology · 2025
    Article
  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chunhui ZhuDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Fang ChenDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Shengmin ZhangDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Hong SheDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Yun JuDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Xidong WenDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Chunxia YangDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Yan SunDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Naijun DongDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Tongmin XueDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Kaifeng LiuDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Feng LiDepartment of Reproductive Medicine Center, Clinical Medical College, Yangzhou University, Yangzhou, China.
Hengmi CuiInstitute of Epigenetics and Epigenomics, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the effect of elevated sperm DNA fragmentation index (DFI) on fresh and frozen embryo transfer cycles. Methods: A retrospective study was performed with 549 fresh embryo transfer cycles and 1340 frozen embryo transfer cycles after Results: The statistical results of 549 fresh embryo transfer cycles showed that the delivery rate in the normal sperm DFI group (43.9% vs. 27.1%, Conclusion: The increase of sperm DFI significantly reduced the delivery rate of fresh embryo transfer cycles and the biochemical pregnancy rate and clinical pregnancy rate of frozen embryo transfer cycles.

Indexed as

Abortion, SpontaneousDNA FragmentationEmbryo TransferFemaleFertilization in VitroHumansMalePregnancyRetrospective StudiesSemenSpermatozoafresh embryo transferfrozen embryo transferintracytoplasmic sperm injectionin vitro fertilizationsperm DNA fragmentation

Identifiers

PMID35909570
PMCPMC9329669

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.