Evidence map›Paper›PMID 35909539›Full record

ArticleFrontiers in endocrinology2022

Children With Short Stature Display Reduced

Federica Tonon, Gianluca Tornese, Fabiola Giudici, Francesca Nicolardi, Barbara Toffoli, Egidio Barbi, Bruno Fabris, Stella Bernardi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Federica TononDepartment of Medical Surgical and Health Sciences, Ospedale di Cattinara, University of Trieste, Trieste, Italy.
Gianluca TorneseInstitute for Maternal and Child Health IRCCS 'Burlo Garofolo', Trieste, Italy.
Fabiola GiudiciDepartment of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.
Francesca NicolardiDepartment of Medical Surgical and Health Sciences, Ospedale di Cattinara, University of Trieste, Trieste, Italy.
Barbara ToffoliDepartment of Medical Surgical and Health Sciences, Ospedale di Cattinara, University of Trieste, Trieste, Italy.
Egidio BarbiDepartment of Medical Surgical and Health Sciences, Ospedale di Cattinara, University of Trieste, Trieste, Italy.
Bruno FabrisDepartment of Medical Surgical and Health Sciences, Ospedale di Cattinara, University of Trieste, Trieste, Italy.
Stella BernardiDepartment of Medical Surgical and Health Sciences, Ospedale di Cattinara, University of Trieste, Trieste, Italy.
Ospedale di Cattinara · ITIRCCS Materno Infantile Burlo Garofolo · ITUniversity of Trieste · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The cause of short stature remains often unknown. The renin-angiotensin system contributes to growth regulation. Several groups reported that angiotensin-converting enzyme 2 ( Materials and Methods: children aged between 2 and 14 years were consecutively recruited in a University Hospital pediatric tertiary care center. Cases were children with short stature defined as height SD ≤ -2 diagnosed with growth hormone deficiency (GHD) or idiopathic short stature (ISS), before any treatment. Exclusion criteria were: acute diseases, kidney disease, endocrine or autoimmune disorders, precocious puberty, genetic syndromes, SGA history. Results: Children with short stature displayed significantly lower Conclusions: Our study confirms the association between the reduction of

Indexed as

Angiotensin-Converting Enzyme 2Dwarfism, PituitaryHuman Growth HormoneCase-Control StudiesGrowth DisordersHumansLeukocytes, MononuclearAngiotensin-Converting Enzyme 2Human Growth HormoneACE2angiotensinANPgrowth hormone deficiencygrowth retardationRenin-Angiotensin Systemshort stature

Identifiers

PMID35909539
PMCPMC9335146
OpenAlexW4285593720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.