Evidence map›Paper›PMID 35909516›Full record

ArticleFrontiers in endocrinology2022

Elevated Adipsin and Reduced C5a Levels in the Maternal Serum and Follicular Fluid During Implantation Are Associated With Successful Pregnancy in Obese Women.

Manjunath Ramanjaneya, Ilhame Diboun, Najeha Rizwana, Yaser Dajani, Lina Ahmed, Alexandra E Butler, Thoraya Ali Almarzooqi, Mohammed Shahata, Moza Khalaf Al Bader, Einas Elgassim and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Diagnostic performance of urinary adipsin as a screening biomarker for pre-eclampsia.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Manjunath RamanjaneyaQatar Metabolic Institute, Hamad Medical Corporation, Doha, Qatar.
Ilhame DibounCollege of Health and Life sciences, Doha, Qatar.
Najeha RizwanaBiomedical Research Center (BRC), Qatar University, Doha, Qatar.
Yaser DajaniReproductive Medicine, Doha, Qatar.
Lina AhmedDepartment of Medicine, Doha, Qatar.
Alexandra E ButlerPost Graduate Studies and Research, Adliya, Bahrain.
Thoraya Ali AlmarzooqiObstetrics and Gynecology Department, Women's Hospital, Hamad Medical Corporation, Doha, Qatar.
Mohammed ShahataObstetrics and Gynecology Department, Women's Hospital, Hamad Medical Corporation, Doha, Qatar.
Moza Khalaf Al BaderObstetrics and Gynecology Department, Women's Hospital, Hamad Medical Corporation, Doha, Qatar.
Einas ElgassimDepartment of Medicine, Doha, Qatar.
Hasan BurjaqObstetrics and Gynecology Department, Women's Hospital, Hamad Medical Corporation, Doha, Qatar.
Stephen L AtkinPost Graduate Studies and Research, Adliya, Bahrain.
Abdul-Badi Abou-SamraQatar Metabolic Institute, Hamad Medical Corporation, Doha, Qatar.
Mohamed A ElrayessBiomedical Research Center (BRC), Qatar University, Doha, Qatar.
Hamad Medical Corporation · QAQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Complement factors mediate the recruitment and activation of immune cells and are associated with metabolic changes during pregnancy. The aim of this study was to determine whether complement factors in the maternal serum and follicular fluid (FF) are associated with Methods: Forty overweight/obese (BMI = 30.8 ± 5.2 kg/m Results: Out of 40 IVF cycles, 14 (35%) resulted in pregnancy. Compared to women with failed pregnancies, women with successful pregnancies had higher levels of adipsin in the serum and FF ( Conclusions: Higher adipsin and lower C5a levels in the maternal serum during implantation are potential markers of successful outcome in obese women undergoing IVF-assisted pregnancies.

Indexed as

Complement C5aComplement Factor DFollicular FluidAdultBiomarkersFemaleHumansObesityOverweightPregnancyPregnancy OutcomeProperdinBiomarkersComplement C5aComplement Factor DProperdinadipsincomplement factorsembryosfollicular fluid (FF)in vitro fertilization (IVF)

Identifiers

PMID35909516
PMCPMC9326155
OpenAlexW4285393422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.