Evidence map›Paper›PMID 35909475›Full record

ArticleBioMed research international2022

Inhibition of

Nair Silva Macêdo, Zildene de Sousa Silveira, Paula Patrícia Marques Cordeiro, Henrique Douglas Melo Coutinho, José Pinto Siqueira Júnior, Lucindo José Quintans Júnior, Abolghasem Siyadatpanah, Bonglee Kim, Francisco Assis Bezerra da Cunha, Márcia Vanusa da Silva

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Frontiers in microbiology · 2024
    Review
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Nair Silva MacêdoGraduate Program in Biological Sciences-PPGCB, Federal University of Pernambuco-UFPE, Recife, PE, Brazil.
Zildene de Sousa SilveiraGraduate Program in Biological Sciences-PPGCB, Federal University of Pernambuco-UFPE, Recife, PE, Brazil.
Paula Patrícia Marques CordeiroLaboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato, CE, Brazil.
Henrique Douglas Melo CoutinhoLaboratory of Microbiology and Molecular Biology (LMBM), Regional University of Cariri-URCA, Crato, CE, Brazil.ORCID https://orcid.org/0000-0002-6634-4207
José Pinto Siqueira JúniorLaboratory of Microorganism Genetics (LGM), Department of Molecular Biology, Federal University of Paraiba-UFPB, Brazil.
Lucindo José Quintans JúniorLaboratory of Neuroscience and Pharmacological Tests-LANEF, Federal University of Sergipe, Aracaju, SE, Brazil.
Abolghasem SiyadatpanahFerdows Paramedical School, Birjand University of Medical Sciences, Birjand, Iran.ORCID https://orcid.org/0000-0003-3172-5939
Bonglee KimDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID https://orcid.org/0000-0002-8678-156X
Francisco Assis Bezerra da CunhaLaboratory of Semi-Arid Bioprospecting (LABSEMA), Regional University of Cariri-URCA, Crato, CE, Brazil.
Márcia Vanusa da SilvaGraduate Program in Biological Sciences-PPGCB, Federal University of Pernambuco-UFPE, Recife, PE, Brazil.
Universidade Federal de Pernambuco · BRUniversidade Regional do Cariri · BRBirjand University of Medical Sciences · IRKyung Hee University · KRUniversidade Federal da Paraíba · BRUniversidade Federal de Sergipe · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Efflux pumps are transmembrane proteins that expel drugs out of a bacterial cell contributing to microorganism drug resistance. Several studies addressing the use of natural products with medicinal properties have intensified given the above. Thus, the aim of the present study was to investigate the antibacterial activity and the O-eugenol potential in Results: O-eugenol presented a MIC of 1024 Conclusions: While we can conclude that the tested product has an efflux pump inhibitory effect, further studies are needed to elucidate its mechanisms of action, in addition to assays using other strains to verify whether the substance has the same inhibitory effect.

Indexed as

Staphylococcal InfectionsStaphylococcus aureusAnimalsAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBacterial ProteinsDrosophila melanogasterEugenolMicrobial Sensitivity TestsModels, AnimalAnti-Bacterial AgentsATP-Binding Cassette, Sub-Family C ProteinsBacterial ProteinsEugenol

Identifiers

PMID35909475
PMCPMC9325621
OpenAlexW4286213951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.