Evidence map›Paper›PMID 35909464›Full record

ArticleFEMS microbes2022

Gram-negative bacteria act as a reservoir for aminoglycoside antibiotics that interact with host factors to enhance bacterial killing in a mouse model of pneumonia.

Christiaan D M Wijers, Ly Pham, Martin V Douglass, Eric P Skaar, Lauren D Palmer, Michael J Noto

Open access · goldAbstract read
In one paragraph

Article in FEMS microbes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Christiaan D M WijersDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, United States.ORCID https://orcid.org/0000-0002-0106-2962
Ly PhamDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, United States.
Martin V DouglassDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, United States.
Eric P SkaarDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, United States.
Lauren D PalmerDepartment of Microbiology and Immunology, University of Illinois Chicago, 835 South Wolcott Avenue, Chicago, IL 60612, United States.
Michael J NotoDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 1161 21st Avenue South, Nashville, TN 37232, United States.
Vanderbilt University Medical Center · USUniversity of Illinois Chicago · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3M
Medical Scientist Training ProgramT32GM152284 · NIGMS · VANDERBILT UNIVERSITY · PI Christopher S. Williams · 2024 to 2026
$4.8M
The Role of Mitochondrial Metabolism in Neutrophilic Lung InflammationR01HL152210 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI NOTO, MICHAEL JAMES · 2020 to 2024
$2.6M
The impact of dietary zinc deficiency on innate immunity to lung infectionR00HL143441 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PALMER, LAUREN DISTERHOFT · 2021 to 2023
$954k
NHLBI NIH HHS R00 HL143441NHLBI NIH HHS R01 HL152210NIGMS NIH HHS T32 GM007347NIGMS NIH HHS T32 GM152284
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

aminoglycosidesantibioticsbacterial pneumoniaGram-negativehost–microbe interactionspulmonary surfactant

Identifiers

PMID35909464
PMCPMC9326624
OpenAlexW4280518879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.