Evidence map›Paper›PMID 35909440›Full record

ArticleJournal of smoking cessation2022

Repetitive Transcranial Magnetic Stimulation for Tobacco Treatment in Cancer Patients: A Preliminary Report of a One-Week Treatment.

Xingbao Li, Benjamin A Toll, Matthew J Carpenter, Paul J Nietert, Morgan Dancy, Mark S George

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Journal of smoking cessation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04903028 narecruitingnot on this map

RTMS Manipulates Imbalanced Drive-reward and Executive Control Circuitry for Smoking Cessation

TypeinterventionalSponsorMedical University of South CarolinaRan2021 to 2027Enrolled64ConditionsTobacco Use, Cigarette SmokingArmsSham rTMS, Active rTMS 10 Hz DLPFC
NCT07050862 narecruitingnot on this mapstarted 2026, after this paper: background citation

Circuity-guided Repetitive Transcranial Magnetic Stimulation (rTMS) for Tobacco Use in Veterans: A Comparison of Insula-rTMS and Prefrontal-rTMS

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2026 to 2030Enrolled56ConditionsTabacco Use Disorder, rTMSArmsTranscranial Magnetic Stimulation, Personalized-image-guided and E-field-modeling dose rTMS (precision TMS)
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Cellular and Molecular Effects of Magnetic Fields.International journal of molecular sciences · 2024
    Review
  4. Brain stimulation therapeutics.Addiction neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xingbao LiDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA.ORCID https://orcid.org/0000-0002-3284-9047
Benjamin A TollHollings Cancer Center Medical University of South Carolina, USA.
Matthew J CarpenterDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA.ORCID https://orcid.org/0000-0002-8909-1302
Paul J NietertDepartment of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA.ORCID https://orcid.org/0000-0002-3933-4986
Morgan DancyDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
Mark S GeorgeDepartment of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA.
Medical University of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Smoking cessation represents a significant opportunity to improve cancer survival rates, reduces the risk of cancer treatment complications, and improves quality of life. However, about half of cancer patients who smoke continue to smoke despite the availability of several treatments. Previous studies demonstrate that repetitive transcranial magnetic stimulation (rTMS) over the left dorsolateral prefrontal cortex (DLPFC) decreases cue craving, reduces cigarette consumption, and increases the quit rate in tobacco use disorder. We investigated whether 5 sessions of rTMS can be safely and efficaciously used for smoking cessation in cancer patients. Methods: We enrolled 11 treatment-seeking smokers with cancer (>5 cigarettes per day) in a randomized, double-blind, sham-controlled proof-of-concept study. Participants received 5 daily sessions of active 10 Hz rTMS of the left DLPFC (3000 pulses per session) or sham rTMS and were followed up for 1 month via phone assessments. Main outcomes included reductions in the number of smoked-cigarettes per day (primary) and craving (secondary). Adverse effects were reported daily by participants. Results: Seven of 11 participants completed 5 sessions of rTMS over one week. Compared to sham treatment ( Conclusions: Five sessions of daily rTMS over the left DLPFC might benefit cancer patients who smoke cigarettes. However, further evidence is needed to determine with more certainty its therapeutic effect and adverse effects for cancer patients who smoke cigarettes.

Identifiers

PMID35909440
PMCPMC9293555
OpenAlexW4285009351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.