Evidence map›Paper›PMID 35909342›Full record

ArticleBone & joint open2022

Who, if anyone, may benefit from a total hip arthroplasty after a displaced femoral neck fracture?: a post hoc subgroup analysis of the HEALTH trial.

Frede Frihagen, Marianne Comeau-Gauthier, Daniel Axelrod, Sofia Bzovsky, Rudolf Poolman, Diane Heels-Ansdell, Mohit Bhandari, Sheila Sprague, Emil Schemitsch, HEALTH Investigators

Open access · goldAbstract read
In one paragraph

Article in Bone & joint open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Frede FrihagenDepartment of Orthopaedic Surgery, Østfold Hospital Trust, Grålum, Norway.ORCID 0000-0002-4811-669X
Marianne Comeau-GauthierDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Canada.ORCID 0000-0002-2317-4172
Daniel AxelrodDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Canada.ORCID 0000-0002-0460-1298
Sofia BzovskyDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Canada.ORCID 0000-0003-3505-1396
Rudolf PoolmanDepartment of Orthopedic Surgery, OLVG, Leiden, the Netherlands.
Diane Heels-AnsdellDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada.ORCID 0000-0003-4362-801X
Mohit BhandariDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Canada.ORCID 0000-0003-0948-637X
Sheila SpragueDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, Canada.ORCID 0000-0003-1466-8063
Emil SchemitschDepartment of Surgery, University of Western Ontario, London, Canada.ORCID 0000-0002-6435-9069
HEALTH Investigators
Impact · CAMcMaster University · CAUniversity of Oslo · NOWestern University · CA

Funding

Hip Fracture Evaluation Alternatives of Total Hip vs Hemi-arthroplasty (HEALTH)UM1AR063386 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI EINHORN, THOMAS A. · 2012 to 2016
$1.1M
NIAMS NIH HHS UM1 AR063386
6 · The paper itself

Abstract

aimsThe aim of this study was to explore the functional results in a fitter subgroup of participants in the Hip Fracture Evaluation with Alternatives of Total Hip Arthroplasty versus Hemiarthroplasty (HEALTH) trial to determine whether there was an advantage of total hip arthroplasty (THA) versus hemiarthroplasty (HA) in this population.

methodsWe performed a post hoc exploratory analysis of a fitter cohort of patients from the HEALTH trial. Participants were aged over 50 years and had sustained a low-energy displaced femoral neck fracture (FNF). The fittest participant cohort was defined as participants aged 70 years or younger, classified as American Society of Anesthesiologists grade I or II, independent walkers prior to fracture, and living at home prior to fracture. Multilevel models were used to estimate the effect of THA versus HA on functional outcomes. In addition, a sensitivity analysis of the definition of the fittest participant cohort was performed.

resultsThere were 143 patients included in the fittest cohort. Mean age was 66 years (SD 4.5) and 103 were female (72%). No clinically relevant differences were found between the treatment groups in the primary and sensitivity analyses.

conclusionThis analysis found no differences in functional outcomes between HA and THA within two years of displaced low-energy FNF in a subgroup analysis of the fittest HEALTH patients. These findings suggest that very few patients above 50 years of age benefit in a clinically meaningful way from a THA versus a HA early after injury.Cite this article:

Indexed as

12-Item Short Form Survey (SF-12)Anesthesiologistsdisplaced femoral neck fractureEQ-5D scoresFemoral neck fracturefunctional outcomesHealth-related quality of lifeHemiarthroplastyhip fracturessensitivity analysisTotal hip arthroplastytotal hip arthroplasty (THA)walkers

Identifiers

PMID35909342
PMCPMC9422900
OpenAlexW4289171812

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.