Evidence map›Paper›PMID 35909029›Full record

Trial reportAmerican journal of preventive medicine2022

A Risk Education Program Decreases Leftover Prescription Opioid Retention: An RCT.

Terri Voepel-Lewis, Carol J Boyd, Alan R Tait, Sean Esteban McCabe, Brian J Zikmund-Fisher

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03287622 (Scenario-tailored Opioid Messaging Program), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03287622 nacompletednot on this map

Scenario-tailored Opioid Messaging Program (STOMP): An Interactive Intervention to Prevent Opioid-related Adverse Drug Events in Children and Adolescents

TypeinterventionalSponsorUniversity of MichiganRan2017 to 2019Enrolled712ConditionsPain, Postoperative, Medication Adherence, Opioid Use, Knowledge, Attitudes, PracticeArmsEducational Intervention, Nudge
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Terri Voepel-LewisSchool of Nursing, University of Michigan, Ann Arbor, Michigan; Department of Anesthesiology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Center for the Study of Drugs, Alcohol, Smoking and Health (DASH Center), University of Michigan, Ann Arbor, Michigan. Electronic address: terriv@umich.edu.
Carol J BoydSchool of Nursing, University of Michigan, Ann Arbor, Michigan; Center for the Study of Drugs, Alcohol, Smoking and Health (DASH Center), University of Michigan, Ann Arbor, Michigan.
Alan R TaitDepartment of Anesthesiology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan; Center for Bioethics and Social Sciences in Medicine, University of Michigan, Ann Arbor, Michigan.
Sean Esteban McCabeSchool of Nursing, University of Michigan, Ann Arbor, Michigan; Center for the Study of Drugs, Alcohol, Smoking and Health (DASH Center), University of Michigan, Ann Arbor, Michigan; Institute for Social Research, University of Michigan, Ann Arbor, Michigan.
Brian J Zikmund-FisherCenter for Bioethics and Social Sciences in Medicine, University of Michigan, Ann Arbor, Michigan; Department of Health Behavior Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan; Internal Medicine, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.
University of Michigan · USMichigan Department of Health and Human Services · US

Funding

Trajectories of Prescription Nonmedical Drug MisuseR01DA031160 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEAN ESTEBAN MCCABE · 2011 to 2026
$3.7M
Scenario-tailored opioid messaging program: An interactive intervention to prevent analgesic-related adverse drugs events in children and adolescentsR01DA044245 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VOEPEL-LEWIS, TERRI DIANE · 2017 to 2019
$2.1M
The Symptom-Associated Pathway to Substance Use and Misuse during AdolescenceR01DA052310 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VOEPEL-LEWIS, TERRI DIANE · 2021 to 2025
$1.9M
NIDA NIH HHS R01 DA031160NIDA NIH HHS R01 DA044245NIDA NIH HHS R01 DA052310
6 · The paper itself

Abstract

introductionRetaining leftover prescription opioids poses the risks of diversion, misuse, overdose, and death for youth and other family members. This study examined whether a new educational program would enhance risk perceptions and disposal intentions among parents and decrease their retention of leftover prescription opioids. STUDY

designThis study is an RCT (NCT03287622). SETTING/

participantsA total of 648 parents whose children were prescribed opioid analgesics were recruited from a Midwestern, academic pediatric hospital between 2017 and 2019. Parents were randomized to receive routine information (control) with or without Scenario-Tailored Opioid Messaging Program intervention.

interventionThe intervention provided opioid risk and mitigation advice using interactive decisional feedback.

main outcome measuresThe main outcome measures were parents' perceptions of the riskiness of keeping/sharing opioids and child misuse measured at baseline, Days 3 and 14, their intention to dispose of leftover opioids, and their final retention decisions after the child's use (at or around Day 14).

resultsPerceived riskiness of child misuse and keeping/sharing opioids increased from baseline through Day 14 only for parents in the intervention group (p≤0.006). However, there were no significant differences in risk perceptions between groups and no intervention effect on disposal intentions at either follow-up. Despite these findings, the intervention reduced the likelihood of parents' opioid retention when adjusted for important parent and child covariates (AOR=0.48; 95% CI=0.25, 0.93; p=0.028). Parents who reported past opioid misuse also showed higher retention behavior (AOR=4.78; 95% CI=2.05, 11.10; p<0.001).

conclusionsA scenario-specific educational intervention emphasizing the potential risks that leftover opioids pose to children and that provided risk mitigation advice decreased parents' retention of their child's leftover opioid medication. Removing leftover prescription drugs from homes with children may be an important step to reducing diversion, accidental poisoning, and misuse among youth.

trial registrationThis study is registered at www. CLINICALTRIALS: gov NCT03287622.

Indexed as

Drug OverdoseOpioid-Related DisordersAdolescentAnalgesics, OpioidChildHumansParentsPrescriptionsAnalgesics, Opioid

Identifiers

PMID35909029
PMCPMC10866200
OpenAlexW4288085207

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.