ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022
Translational Organic Neural Interface Devices at Single Neuron Resolution.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Optimal inter-electrode distances for maximizing single unit yield per electrode in neural recordings.Microsystems & nanoengineering · 2026Article
- Implantable bioelectronics for gut electrophysiology.Nature communications · 2025Article
- Contorted acene ribbons for stable and ultrasensitive neural probes.Science advances · 2025Article
- Stable, chronic in-vivo recordings from a fully wireless subdural-contained 65,536-electrode brain-computer interface device.bioRxiv : the preprint server for biology · 2025Article
- Spatial control of doping in conducting polymers enables complementary, conformable, implantable internal ion-gated organic electrochemical transistors.Nature communications · 2025Article
- E-Suture: Mixed-Conducting Suture for Medical Devices.Advanced healthcare materials · 2024Article
- High-Density, Conformable Conducting Polymer-Based Implantable Neural Probes for the Developing Brain.Advanced healthcare materials · 2024Article
- Applications of 2D Nanomaterials in Neural Interface.International journal of molecular sciences · 2024Review
- Modified Neuropixels probes for recording human neurophysiology in the operating room.Nature protocols · 2023Review
- Plant electrophysiology with conformable organic electronics: Deciphering the propagation of Venus flytrap action potentials.Science advances · 2023Article
- Large-scale, closed-loop interrogation of neural circuits underlying cognition.Trends in neurosciences · 2022Review
- Translational Organic Neural Interface Devices at Single Neuron Resolution.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 1 country.
Funding
Abstract
Recording from the human brain at the spatiotemporal resolution of action potentials provides critical insight into mechanisms of higher cognitive functions and neuropsychiatric disease that is challenging to derive from animal models. Here, organic materials and conformable electronics are employed to create an integrated neural interface device compatible with minimally invasive neurosurgical procedures and geared toward chronic implantation on the surface of the human brain. Data generated with these devices enable identification and characterization of individual, spatially distribute human cortical neurons in the absence of any tissue penetration (n = 229 single units). Putative single-units are effectively clustered, and found to possess features characteristic of pyramidal cells and interneurons, as well as identifiable microcircuit interactions. Human neurons exhibit consistent phase modulation by oscillatory activity and a variety of population coupling responses. The parameters are furthermore established to optimize the yield and quality of single-unit activity from the cortical surface, enhancing the ability to investigate human neural network mechanisms without breaching the tissue interface and increasing the information that can be safely derived from neurophysiological monitoring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.