Evidence map›Paper›PMID 35908778›Full record

ArticleJournal of clinical laboratory analysis2022

Correlation analysis between vitamin A, D, and E status with altitude, seasonal variation, and other factors, among children aged 0-6 years in a Chinese population living in the Tibetan plateau of Ganzi prefecture.

Ping Huang, Gang Ke, Xinmei Lin, Quansheng Wang, Wei Lu, Li Zeng, Shiying Xu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Ping HuangDepartment of Child Healthcare, Luzhou people's Hospital, Luzhou, China.ORCID https://orcid.org/0000-0003-3645-6950
Gang KeDepartment of Pharmacy, Luzhou people's Hospital, Luzhou, China.
Xinmei LinDepartment of Blood Transfusion, Luzhou people's Hospital, Luzhou, China.
Quansheng WangDepartment of Rehabilitation, Luxian Hospital of TCM, Luzhou, China.
Wei LuDepartment of Rehabilitation, Luzhou People's Hospital, Luzhou, China.
Li ZengDepartment of Emergency, Luzhou People's Hospital, Luzhou, China.
Shiying XuDepartment of Pharmacy, Luzhou people's Hospital, Luzhou, China.
First Affiliated Hospital of Sichuan Medical University · CNCM Hospital · KRSouthwest Medical University · CN

Funding

Health and family planning research project of sichuan province 17PJ276
6 · The paper itself

Abstract

objectiveWe attempted to understand the status of vitamin (Vit) A, D, and E in children aged 0-6 living in the Tibetan plateau areas of Ganzi prefecture, to provide the basis for relevant government departments to carry out physical examinations of these children and to prevent and cure four key diseases (Infantile diarrhea, nutritional anemia, rickets, and infantile pneumonia).

methodsSerum retinol and tocopherol levels were detected using high-performance liquid chromatography (HPLC). Serum levels of 25-(OH)D were detected by high-performance liquid chromatography-tandem mass spectrometry (LC-MS). The polynomial logistic regression was used to analyze the effects of age, season, altitude, and gender on Vit A, D, and E levels.

resultsVit A and D had the lowest mean serum levels before the age of 1 year and with the most significant deficiency rates. The lowest Vit E levels were seen in the Toddlerhood group. The rates of deficiency and insufficiency were the highest. Vit A, D, and E levels were significantly affected by seasonal changes and were significantly higher in the summer than in any other season. Vit A and D were significantly affected by altitude, and their levels were lowest above 4 km.

conclusionThe overall levels of Vit A, D, and E in children aged 0-6 in the Tibetan plateau areas of Ganzi prefecture were lower than those in the plain's areas.

Indexed as

Vitamin AVitamin D DeficiencyAltitudeAsian PeopleChildHumansSeasonsTibetVitamin DVitamin AVitamin D25-hydroxy vitamin Daltitudeplateau Tibetansseasonal variationvitamin avitamin E

Identifiers

PMID35908778
PMCPMC9459275
OpenAlexW4289109271

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.