Evidence map›Paper›PMID 35908740›Full record

ArticleUrology2022

Automated Machine Learning Segmentation and Measurement of Urinary Stones on CT Scan.

Rilwan Babajide, Katerina Lembrikova, Justin Ziemba, James Ding, Yuemeng Li, Antoine Selman Fermin, Yong Fan, Gregory E Tasian

Abstract read
In one paragraph

Article in Urology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  13. Theranostic roles of machine learning in clinical management of kidney stone disease.Computational and structural biotechnology journal · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rilwan BabajideUniversity of Chicago Pritzker School of Medicine, Chicago, IL.
Katerina LembrikovaSUNY Downstate College of Medicine, Brooklyn, NY.
Justin ZiembaUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Department of Surgery, Division of Urology, Hospital of the University of Pennsylvania, Philadelphia, PA.
James DingUniversity of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Yuemeng LiDepartment of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; The Center for Biomedical Image Computing and Analytics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Antoine Selman FerminDepartment of Surgery, Division of Pediatric Urology, The Children's Hospital of Philadelphia, Philadelphia, PA.
Yong FanDepartment of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; The Center for Biomedical Image Computing and Analytics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Gregory E TasianDepartment of Surgery, Division of Pediatric Urology, The Children's Hospital of Philadelphia, Philadelphia, PA; Department of Biostatistics, Epidemiology, and Informatics; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Electronic address: tasiang@chop.edu.

Funding

Center for Machine Learning in Urology-Scientific ProjectP20DK127488 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI TASIAN, GREGORY EDWARD · 2020 to 2021
$691k
NIDDK NIH HHS P20 DK127488
6 · The paper itself

Abstract

objectivesTo evaluate the performance of an engineered machine learning algorithm to identify kidney stones and measure stone characteristics without the need for human input.

methodsWe performed a cross-sectional study of 94 children and adults who had kidney stones identified on non-contrast CT. A previously developed deep learning algorithm was trained to segment renal anatomy and kidney stones and to measure stone features. The performance and speed of the algorithm to measure renal anatomy and kidney stone features were compared to the current gold standard of human measurement performed by 3 independent reviewers.

resultsThe algorithm was 100% sensitive and 100% specific in detecting individual kidney stones. The mean stone volume segmented by the algorithm was smaller than that of human reviewers and had moderate overlap (Dice score: 0.66). There was substantial variation between human reviewers in total segmented stone volume (Jaccard score: 0.17) and volume of the single largest stone (Jaccard score: 0.33). Stone segmentations performed by the machine learning algorithm more precisely approximated stone borders than those performed by human reviewers on qualitative assessment.

conclusionAn engineered machine learning algorithm can identify and characterize stones more accurately and reliably than humans, which has the potential to improve the precision and efficiency of assessing kidney stone burden.

Indexed as

Kidney CalculiUrinary CalculiAdultChildCross-Sectional StudiesHumansMachine LearningTomography, X-Ray Computed

Identifiers

PMID35908740
PMCPMC9936246

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.