Evidence map›Paper›PMID 35908724›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022

Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil.

Jacqueline Ferreira de Oliveira, Renata Eliane de Ávila, Neimy Ramos de Oliveira, Natália da Cunha Severino Sampaio, Maiara Botelho, Fabíola Araújo Gonçalves, Cirilo José Ferreira Neto, Ana Carolina de Almeida Milagres, Tatiane Cristina Caldeira Gomes, Tássia Lopardi Pereira and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 5 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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  17. Long-Term Quality of Life after COVID-19 Infection: Cross-Sectional Study of Health Care Workers.International journal of environmental research and public health · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Jacqueline Ferreira de OliveiraInfectious Disease Division, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil. Electronic address: jacfoliveira@yahoo.com.br.
Renata Eliane de ÁvilaInfectious Disease Division, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil.
Neimy Ramos de OliveiraCritical Care Unit, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil.
Natália da Cunha Severino SampaioCritical Care Unit, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil.
Maiara BotelhoEpidemiology Division, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil.
Fabíola Araújo GonçalvesEpidemiology Division, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil.
Cirilo José Ferreira NetoInfectious Disease Division, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil.
Ana Carolina de Almeida MilagresInfectious Disease Division, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil.
Tatiane Cristina Caldeira GomesCritical Care Unit, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil.
Tássia Lopardi PereiraInfectious Disease Division, Eduardo de Menezes Hospital, Fundação Hospitalar do Estado de Minas Gerais, Belo Horizonte, Brazil.
Renan Pedra de SouzaIntegrative Biology Laboratory, Genetics, Ecology and Evolution Department, Biological Science Institute, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Israel MolinaRené Rachou Institute - Fiocruz Minas, Belo Horizonte, Brazil.
Fundação Hospitalar do Estado de Minas Gerais · BRFundação Oswaldo Cruz · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCOVID-19 has been associated with long-term consequences to patient wellness and quality of life. Data on post-COVID-19 conditions are scarce in developing countries. This study aimed to investigate long COVID in a cohort of hospitalized patients in Brazil.

methodsSurviving patients discharged from the hospital between July 1, 2020 and March 31, 2021 were assessed between 2 and 12 months after acute onset of COVID-19. The outcomes were the prevalence of persistent symptoms, risk factors associated with long COVID, and quality of life as assessed by the EuroQol 5D-3L questionnaire.

resultsOf 439 participants, most (84%) reported at least one long COVID symptom, at a median of 138 days (interquartile range [IQR] 90-201) after disease onset. Fatigue (63.1%), dyspnea (53.7%), arthralgia (56.1%), and depression/anxiety (55.1%) were the most prevalent symptoms. In multivariate analysis, dysgeusia (odds ratio [OR] 2.0, 95% confidence interval [CI] 1.18-3.44, P <0.001) and intensive care unit (ICU) admission (OR 2.6, 95% CI 1.19-6.56, P = 0.03) were independently associated with long COVID. Fifty percent of patients reported a worsened clinical condition and quality of life.

conclusionLong-term outcomes of SARS-CoV-2 infection in a low- to middle-income country were relevant. Fatigue was the most common persistent symptom. ICU admission was an independent factor associated with long COVID. Dysgeusia could be a potential predictor of long COVID.

Indexed as

COVID-19BrazilCross-Sectional StudiesDysgeusiaFatigueHumansPost-Acute COVID-19 SyndromeQuality of LifeRisk FactorsSARS-CoV-2BrazilCOVID-19DysgeusiaLong COVIDQuality of lifeRisk factors

Identifiers

PMID35908724
PMCPMC9330427
OpenAlexW4288455761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.