Evidence map›Paper›PMID 35908721›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2022

Multisystem inflammatory syndrome in a young adult successfully treated with plasmapheresis, immunoglobulins, and corticosteroids: a case report.

Miodrag Sreckovic, Ruzica Radojevic Marjanovic, Biljana Popovska Jovicic, Slobodan Jankovic, Rasa Medovic, Milica Begovic Cvetkovic, Tatjana Lazarevic, Milos Milosavljevic, Stefan Simovic, Rada Vucic

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Miodrag SreckovicDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, Serbia; Clinic for Cardiology, University Clinical Center Kragujevac, Kragujevac, Serbia.
Ruzica Radojevic MarjanovicClinic for Infectious Diseases, University Clinical Center Kragujevac, Kragujevac, Serbia.
Biljana Popovska JovicicClinic for Infectious Diseases, University Clinical Center Kragujevac, Kragujevac, Serbia; Department of Infectious Diseases, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.
Slobodan JankovicDepartment of Pharmacology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Department of Pharmacology, University Clinical Center Kragujevac, Kragujevac, Serbia.
Rasa MedovicDepartment of Pediatrics, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Department of Pediatrics, University Clinical Center Kragujevac, Kragujevac, Serbia.
Milica Begovic CvetkovicDepartment for Rheumatology, Clinic for Internal Medicine, University Clinical Center Kragujevac, Kragujevac, Serbia.
Tatjana LazarevicDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, Serbia; Department of Emergency Medicine, University Clinical Center Kragujevac, Kragujevac, Serbia.
Milos MilosavljevicDepartment of Pathology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia; Department of Pathology, University Clinical Center Kragujevac, Kragujevac, Serbia.
Stefan SimovicDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, Serbia; Clinic for Cardiology, University Clinical Center Kragujevac, Kragujevac, Serbia. Electronic address: simovicst@gmail.com.
Rada VucicDepartment of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, Serbia; Clinic for Cardiology, University Clinical Center Kragujevac, Kragujevac, Serbia.
University of Kragujevac · RSClinical Centre of Kragujevac · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel condition named multisystem inflammatory syndrome has raised the alarm worldwide and is leading to severe illness and long-term effects in the post-COVID era. This condition includes infection with fever, abdominal symptoms, acute cardiac injury, and shock. It has similarities with severe forms of Kawasaki disease (KD). In this study, we present a case of a 20-year-old male patient with multisystem inflammatory syndrome associated with COVID-19 infection who was successfully treated with plasmapheresis, immunoglobulins, and steroids for 4 h/day without heparinization or ultrafiltration. Plasmapheresis represents a therapeutic option for KD in patients with all other therapeutic strategies that have failed. However, there is no evidence from controlled clinical trials confirming this option. In our case, plasmapheresis was beneficial in stabilizing and improving the patient's clinical condition. Given the pathophysiological and therapeutic similarities between KD and multisystem inflammatory syndrome, it could be considered a therapeutic option.

Indexed as

COVID-19Mucocutaneous Lymph Node SyndromeAdrenal Cortex HormonesAdultHumansImmunoglobulins, IntravenousMalePlasmapheresisSystemic Inflammatory Response SyndromeYoung AdultAdrenal Cortex HormonesImmunoglobulins, IntravenousCOVID-19Multisystem inflammatory syndromePlasmapheresis

Identifiers

PMID35908721
PMCPMC9331018
OpenAlexW4288458725

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.