ReviewNeuroscience and biobehavioral reviews2022
Prefrontal circuits guiding social preference: Implications in autism spectrum disorder.
Review in Neuroscience and biobehavioral reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Autism spectrum disorder across the lifespan: Dynamic symptom trajectories and multidimensional support framework.Molecular psychiatry · 2026Review
- Dysregulated GluA2-Y876 phosphorylation contributes to loss of synaptic upscaling in GRIP1 mutant mice with reduced sociability and increased repetitive behavior.Molecular psychiatry · 2026Article
- Selective observation following betrayal shapes the social inference landscape.PLoS computational biology · 2026Article
- Article
- Leveraging AI-Driven Neuroimaging Biomarkers for Early Detection and Social Function Prediction in Autism Spectrum Disorders: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Regulation of perisomatic synapses from cholecystokinin basket interneurons through NrCAM and Ankyrin B.Current research in neurobiology · 2025Article
- Neural mechanisms underlying strain preference behaviour and plasticity in mice.Scientific reports · 2025Article
- Postnatal Allergic Inhalation Induces Glial Inflammation in the Olfactory Bulb and Leads to Autism-Like Traits in Mice.International journal of molecular sciences · 2024Article
- Reduced excitatory activity in the developing mPFC mediates a PVTranslational psychiatry · 2024Article
- Dopamine D1 receptor in medial prefrontal cortex mediates the effects of TAAR1 activation on chronic stress-induced cognitive and social deficits.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Gamma frequency connectivity in frontostriatal networks associated with social preference is reduced with traumatic brain injury.Network neuroscience (Cambridge, Mass.) · 2024Article
- Impaired effective functional connectivity in the social preference of children with autism spectrum disorder.Frontiers in neuroscience · 2024Article
- Pre- and postsynaptic N-methyl-D-aspartate receptors are required for sequential printing of fear memory engrams.iScience · 2023Article
- Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice.Brain, behavior, and immunity · 2023Article
- Diminished activity-dependent BDNF signaling differentially causes autism-like behavioral deficits in male and female mice.Frontiers in psychiatry · 2023Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Although Autism Spectrum Disorder (ASD) is increasing in diagnostic prevalence, treatment options are inadequate largely due to limited understanding of ASD's underlying neural mechanisms. Contributing to difficulties in treatment development is the vast heterogeneity of ASD, from physiological causes to clinical presentations. Recent studies suggest that distinct genetic and neurological alterations may converge onto similar underlying neural circuits. Therefore, an improved understanding of neural circuit-level dysfunction in ASD may be a more productive path to developing broader treatments that are effective across a greater spectrum of ASD. Given the social preference behavioral deficits commonly seen in ASD, dysfunction in circuits mediating social preference may contribute to the atypical development of social cognition. We discuss some of the animal models used to study ASD and examine the function and effects of dysregulation of the social preference circuits, notably the medial prefrontal cortex-amygdala and the medial prefrontal cortex-nucleus accumbens circuits, in these animal models. Using the common circuits underlying similar behavioral disruptions of social preference behaviors as an example, we highlight the importance of identifying disruption in convergent circuits to improve the translational success of animal model research for ASD treatment development.
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Registered trials
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