Evidence map›Paper›PMID 35908318›Full record

ArticleCell calcium2022

Ca

Constanza Feliziani, Macarena Fernandez, Gonzalo Quassollo, Deborah Holstein, Sebastián M Bairo, James C Paton, Adrienne W Paton, Juan de Batista, James D Lechleiter, Mariana Bollo

Open access · greenAbstract read
In one paragraph

Article in Cell calcium, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. The mutual interaction of TRPC5 channel with polycystin proteins.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Editorial: The evolving picture of CaFrontiers in physiology · 2023
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Constanza FelizianiInstituto de Investigación Médica M y M Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, 2434 Friuli, Córdoba 5016, Argentina.
Macarena FernandezInstituto de Investigación Médica M y M Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, 2434 Friuli, Córdoba 5016, Argentina.
Gonzalo QuassolloInstituto de Investigación Médica M y M Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, 2434 Friuli, Córdoba 5016, Argentina.
Deborah HolsteinDepartment of Cell Systems and Anatomy, UT Health San Antonio, 8403 Floyd Curl Dr., San Antonio, TX 78229-3904, United States of America.
Sebastián M BairoInstituto de Investigación Médica M y M Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, 2434 Friuli, Córdoba 5016, Argentina.
James C PatonResearch Centre for Infectious Diseases, School of Molecular and Biomedical Science, University of Adelaide, South Australia 5005, Australia.
Adrienne W PatonResearch Centre for Infectious Diseases, School of Molecular and Biomedical Science, University of Adelaide, South Australia 5005, Australia.
Juan de BatistaInstituto Universitario de Ciencias Biomédicas de Córdoba (IUCBC), Hospital Privado Universitario de Córdoba, 420 Naciones Unidas, Córdoba 5016, Argentina.
James D LechleiterDepartment of Cell Systems and Anatomy, UT Health San Antonio, 8403 Floyd Curl Dr., San Antonio, TX 78229-3904, United States of America.
Mariana BolloInstituto de Investigación Médica M y M Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, 2434 Friuli, Córdoba 5016, Argentina. Electronic address: mbollo@immf.uncor.edu.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARThe University of Adelaide · AUThe University of Texas Health Science Center at San Antonio · USHospital Privado · AR

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Regulation of ER-stress Activated UPR kinase PERK in Neurodegenerative DiseasesRF1AG058778 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LECHLEITER, JAMES D · 2019 to 2019
$2.6M
Regulation of the Unfolded Protein Response after Acute Brain InjuryR21NS085732 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LECHLEITER, JAMES D · 2013 to 2014
$369k
NCI NIH HHS P30 CA054174NIA NIH HHS RF1 AG058778NINDS NIH HHS R21 NS085732
6 · The paper itself

Abstract

The accumulation of unfolded proteins within the Endoplasmic Reticulum (ER) activates a signal transduction pathway termed the unfolded protein response (UPR), which attempts to restore ER homoeostasis. If this cannot be done, UPR signalling ultimately induces apoptosis. Ca

Indexed as

eIF-2 KinaseEndoplasmic Reticulum StressApoptosisEndoplasmic ReticulumHumansSignal TransductionUnfolded Protein ResponseeIF-2 KinaseCalcium signallingInositol triphosphate receptor(PKR)-like-ER kinase (PERK)TransloconUnfolded protein response

Identifiers

PMID35908318
PMCPMC9982837
OpenAlexW4286252310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.