Evidence map›Paper›PMID 35908095›Full record

ArticleBiomechanics and modeling in mechanobiology2022

Anorectal volume-pressure relations, contraction work, and flow during defecation.

Hans Gregersen, Yanmin Wang, Fred Field, Mengjun Wang, Kar Man Lo, Xiaomei Guo, William Combs, Ghassan S Kassab

Abstract read
In one paragraph

Article in Biomechanics and modeling in mechanobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Fecobionics in proctology: review and perspectives.Surgery open digestive advance · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hans GregersenCalifornia Medical Innovations Institute, 11107 Roselle St., San Diego, CA, 92121, USA. hag@giome.org.ORCID http://orcid.org/0000-0002-5792-2845
Yanmin WangCalifornia Medical Innovations Institute, 11107 Roselle St., San Diego, CA, 92121, USA.
Fred Field3DT, San Diego, CA, USA.
Mengjun Wang3DT, San Diego, CA, USA.
Kar Man LoCalifornia Medical Innovations Institute, 11107 Roselle St., San Diego, CA, 92121, USA.
Xiaomei GuoCalifornia Medical Innovations Institute, 11107 Roselle St., San Diego, CA, 92121, USA.
William Combs3DT, San Diego, CA, USA.
Ghassan S KassabCalifornia Medical Innovations Institute, 11107 Roselle St., San Diego, CA, 92121, USA.

Funding

Neurophysiological mechanism in sacral neuromodulation in patients suffering from fecal incontinenceOT2OD028203 · OD · CALIFORNIA MEDICAL INNOVATIONS INSTITUTE · PI GREGERSEN, HANS · 2019 to 2021
$3.1M
NIH HHS OT2 OD028203NIH HHS OT2ODO28203
6 · The paper itself

Abstract

Fecobionics is an integrated device that has shown promise for assessment of anorectal function. We used a wireless Fecobionics prototype to visualize defecatory patterns and to compute volume-pressure, contraction work, and flow. Twelve normal subjects were studied. The probe was 10 cm-long and contained pressure sensors and electrodes for impedance planimetry. Pressures, diameters, and volume data during defecation were analyzed. The bag was distended inside rectum to the urge-to-defecate level where after the subjects were asked to evacuate. The contraction work and defecatory flow were computed from the volume changes during expulsion. The minimum anal diameter during the evacuation was 17.6 ± 1.5 mm. The middle diameter recording was 10-20% lower than the front diameter channels and 10-20% bigger than the rear channels. The bag volume at urge correlated with the minimum diameter (r = 0.63). The diameter-pressure and volume-pressure loops were counterclockwise with phases of bag filling, isometric contraction, ejection and anal passage. The defecatory contraction work was 3520 ± 480 mL × cmH

Indexed as

Anal CanalDefecationHumansIsometric ContractionManometryRectumAnorectal functionContraction workDefecatoryFecobionicsFlowPressure–volume

Identifiers

PMID35908095
PMCPMC9633562

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.