Evidence map›Paper›PMID 35908066›Full record

ArticleCell death & disease2022

Germline FOXJ2 overexpression causes male infertility via aberrant autophagy activation by LAMP2A upregulation.

Fu-Rong Bai, Qi-Qian Wu, Yu-Jie Wu, Yan-Qin Hu, Zhi-Xuan Jiang, Hao Lv, Wen-Zhe Qian, Chang Cai, Jing-Wen Wu

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Autophagy andFrontiers in cellular and infection microbiology · 2026
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  6. Characteristic analysis of NBMC genomics · 2025
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  10. Review
  11. Transcriptome Studies Reveal theAnimals : an open access journal from MDPI · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Fu-Rong Bai *Department of Histoembryology, Genetics and Developmental Biology, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China.
Qi-Qian Wu *Department of Histoembryology, Genetics and Developmental Biology, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China.ORCID 0000-0002-1882-7503
Yu-Jie WuDepartment of Histoembryology, Genetics and Developmental Biology, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China.
Yan-Qin HuDepartment of Histoembryology, Genetics and Developmental Biology, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China.
Zhi-Xuan JiangSchool of Medicine, Shanghai Jiao Tong University, 200025, Shanghai, China.
Hao LvSchool of Medicine, Shanghai Jiao Tong University, 200025, Shanghai, China.
Wen-Zhe QianSchool of Medicine, Shanghai Jiao Tong University, 200025, Shanghai, China.
Chang CaiSchool of Medicine, Shanghai Jiao Tong University, 200025, Shanghai, China.
Jing-Wen WuDepartment of Histoembryology, Genetics and Developmental Biology, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China. zpwujw@shsmu.edu.cn.ORCID 0000-0003-0939-511X
Shanghai Jiao Tong University · CNShanghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spermatogenesis is a complex biological process that produces haploid spermatozoa and requires precise regulation by many tissue-specific factors. In this study, we explored the role and mechanism of Fork head box J2 (FOXJ2, which is highly expressed in spermatocytes) in the regulation of spermatogenesis using a germline-specific conditional Foxj2 knock-in mouse model (Stra8-Cre; Foxj2

Indexed as

Infertility, MaleSpermatogenesisAnimalsAutophagyForkhead Transcription FactorsHumansLysosomal-Associated Membrane Protein 2MaleMeiosisMiceSpermatocytesTestisUp-RegulationForkhead Transcription FactorsFOXJ2 protein, humanLysosomal-Associated Membrane Protein 2

Identifiers

PMID35908066
PMCPMC9338950
OpenAlexW4288760570

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.