ArticleJournal of advanced research2023
Whole genome analyses reveal novel genes associated with chicken adaptation to tropical and frigid environments.
Article in Journal of advanced research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 72 citations in OpenAlex.
- Comparative genomic and evolutionary analysis of the heat shock protein gene family in the chicken genome.Animal biotechnology · 2026Article
- Revealing the Shared Genetic Basis of Thermal Adaptation and Abdominal Adiposity in Wenchang Chicken Using Whole-Genome Structural Variation Analysis.Animals : an open access journal from MDPI · 2026Article
- Genome-wide variation landscape reveals temperature adaptation in Chinese indigenous cattle.Journal of animal science and biotechnology · 2026Article
- Genomic signatures of environmental adaptation in Danzhou chickens.BMC genomics · 2026Article
- Mixed Outcomes in Recombination Rates After Domestication: Revisiting Theory and Data.Molecular ecology · 2025Review
- Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Colonization patterns of intestinal pioneering microbiota of different broiler breeds and their effects on composition of intestinal mucosal barrier during early life.Science China. Life sciences · 2025Article
- Multi-omics analysis of gut-organ axes reveals the high-altitude adaptation in Tibetan chicken.iMetaOmics · 2025Article
- Haplotype-resolved genome and pan-genome graphs reveal the impacts of structural variation on functional genome and feather colors in chickens.iMetaOmics · 2025Article
- Whole-genome resequencing revealed genetic structure and specific breed identification loci of Ningxia Jingyuan chicken breed (Gallus gallus).BMC genomics · 2025Article
- Genome-environment association analysis reveals climate-driven adaptation of chickens.Genetics, selection, evolution : GSE · 2025Article
- Research on the Historical Dynamics of Baicheng Oil Chicken Populations.Animals : an open access journal from MDPI · 2025Article
- Comparison of unique Dong Tao chickens from Vietnam and Thailand: genetic background and differences for resource management.Genes & genomics · 2025Article
- Molecular Pathogenesis of Avian Splenic Injury Under Thermal Challenge: Integrated Mitigation Strategies for Poultry Heat Stress.Current issues in molecular biology · 2025Review
- Whole-Genome Sequencing Identifies Functional Genes for Environmental Adaptability in Chinese Geese.Animals : an open access journal from MDPI · 2025Article
- - Invited Review - Challenges and constraints to the sustainability of poultry farming in China.Animal bioscience · 2025Article
- Whole-Genome Resequencing in Sheep: Applications in Breeding, Evolution, and Conservation.Genes · 2025Review
- Multi-Omics Profiling of Lipid Variation and Regulatory Mechanisms in Poultry Breast Muscles.Animals : an open access journal from MDPI · 2025Article
- Article
- Omics in mini-livestock: a genomic perspective on the future of sustainable food systems.Frontiers in genetics · 2025Review
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Authors and funding
16 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionInvestigating the genetic footprints of historical temperature selection can get insights to the local adaptation and feasible influences of climate change on long-term population dynamics. OBJECT: Chicken is a significative species to study genetic adaptation on account of its similar domestication track related to human activity with the most diversified varieties. Yet, few studies have demonstrated the genetic signatures of its adaptation to naturally tropical and frigid environments.
methodHere, we generated whole genome resequencing of 119 domesticated chickens in China including the following breeds which are in order of breeding environmental temperature from more tropical to more frigid: Wenchang chicken (WCC), green-shell chicken (GSC), Tibetan chicken (TBC), and Lindian chicken (LDC).
resultsOur results showed WCC branched off earlier than LDC with an evident genetic admixture between WCC and LDC, suggesting their closer genetic relationship. Further comparative genomic analyses solute carrier family 33 member 1 (SLC33A1) and thyroid stimulating hormone receptor (TSHR) genes exhibited stronger signatures for positive selection in the genome of the more tropical WCC. Furthermore, genotype data from about 3,000 African local ecotypes confirmed that allele frequencies of single nucleotide polymorphisms (SNPs) in these 2 genes appeared strongly associated with tropical environment adaptation. In addition, the NADH:ubiquinone oxidoreductase subunit S4 (NDUFS4) gene exhibited a strong signature for positive selection in the LDC genome, and SNPs with marked allele frequency differences indicated a significant relationship with frigid environment adaptation.
conclusionOur findings partially clarify how selection footprints from environmental temperature stress can lead to advantageous genomic adaptions to tropical and frigid environments in poultry and provide a valuable resource for selective breeding of chickens.
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