Evidence map›Paper›PMID 35907357›Full record

ArticleColloids and surfaces. B, Biointerfaces2022

Single-particle detection of native SARS-CoV-2 virions by microfluidic resistive pulse sensing.

Zoltán Varga, Mónika Madai, Gábor Kemenesi, Tamás Beke-Somfai, Ferenc Jakab

Abstract read
In one paragraph

Article in Colloids and surfaces. B, Biointerfaces, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zoltán VargaBiological Nanochemistry Research Group, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary. Electronic address: varga.zoltan@ttk.hu.
Mónika MadaiNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Ifjúság Útja 20, H-7624 Pécs, Hungary.
Gábor KemenesiNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Ifjúság Útja 20, H-7624 Pécs, Hungary.
Tamás Beke-SomfaiBiological Nanochemistry Research Group, Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
Ferenc JakabNational Laboratory of Virology, Szentágothai Research Centre, University of Pécs, Ifjúság Útja 20, H-7624 Pécs, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microfluidic resistive pulse sensing (MRPS) was used to determine the size -distribution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) based on detecting nearly 30,000 single virions. However, the ultrastructure of SARS-CoV-2 is thoroughly described, but ensemble properties of SARS-CoV-2, e.g., its particle size distribution, are sparsely reported. According to the MRPS results, the size distribution of SARS-CoV-2 follows a log-normal function with a mean value of 85.1 nm, which corresponds to an approximate diameter of the viral envelope. This result also confirms the low number (< 50) of spike proteins on the surface of the virions.

Indexed as

COVID-19SARS-CoV-2HumansMicrofluidicsSpike Glycoprotein, CoronavirusVirionSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2Resistive pulse sensingSARS-CoV-2Size distributionSpike proteinViral envelope

Identifiers

PMID35907357
PMCPMC9306222

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.