Evidence map›Paper›PMID 35907100›Full record

ArticleEJNMMI physics2022

DeepPVC: prediction of a partial volume-corrected map for brain positron emission tomography studies via a deep convolutional neural network.

Keisuke Matsubara, Masanobu Ibaraki, Toshibumi Kinoshita, Alzheimer’s Disease Neuroimaging Initiative

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Article in EJNMMI physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Keisuke MatsubaraDepartment of Management Science and Engineering, Faculty of System Science and Technology, Akita Prefectural University, 84-4 Aza Ebinokuchi Tsuchiya, Yurihonjo, 015-0055, Japan. matsubara@akita-pu.ac.jp.ORCID http://orcid.org/0000-0003-1823-1651
Masanobu IbarakiDepartment of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels, Akita Cerebrospinal and Cardiovascular Center, Akita, 010-0874, Japan.
Toshibumi KinoshitaDepartment of Radiology and Nuclear Medicine, Research Institute for Brain and Blood Vessels, Akita Cerebrospinal and Cardiovascular Center, Akita, 010-0874, Japan.
Alzheimer’s Disease Neuroimaging Initiative

Funding

Research Institute for Brain and Blood Vessels - Akita 19-05
6 · The paper itself

Abstract

backgroundPartial volume correction with anatomical magnetic resonance (MR) images (MR-PVC) is useful for accurately quantifying tracer uptake on brain positron emission tomography (PET) images. However, MR segmentation processes for MR-PVC are time-consuming and prevent the widespread clinical use of MR-PVC. Here, we aimed to develop a deep learning model to directly predict PV-corrected maps from PET and MR images, ultimately improving the MR-PVC throughput.

methodsWe used MR T1-weighted and [

resultsA high SSIM (0.884 ± 0.021) and ICC (0.921 ± 0.042) were observed in the validation and test data (SSIM, 0.876 ± 0.028; ICC, 0.894 ± 0.051). The computation time required to predict a PV-corrected map for a participant (48 s without a graphics processing unit) was much shorter than that for the RBV PVC and MR segmentation processes.

conclusionThese results suggest that the deepPVC model directly predicts PV-corrected maps from MR and PET images and improves the throughput of MR-PVC by skipping the MR segmentation processes.

Indexed as

AmyloidDeep learningPartial volume correctionPET

Identifiers

PMID35907100
PMCPMC9339068

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.