Evidence map›Paper›PMID 35907092›Full record

ArticleSports medicine - open2022

Impact of Ageing on Female Metabolic Flexibility: A Cross-Sectional Pilot Study in over-60 Active Women.

Jordi Monferrer-Marín, Ainoa Roldán, Pablo Monteagudo, Iván Chulvi-Medrano, Cristina Blasco-Lafarga

Registry-linked trialAbstract read
In one paragraph

Article in Sports medicine - open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06336070 (Postmenopausal Oncological Women Exercising for Recover Their Health. Associations and Changes in Metabolic Flexibility and Autonomic Control After Two Training Programs), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06336070 narecruitingnot on this mapstarted 2024, after this paper: background citation

Postmenopausal Oncological Women Exercising for Recover Their Health. Associations and Changes in Metabolic Flexibility and Autonomic Control After Two Training Programs (Muscle Power vs Metabolic Power): the POWER Health Study

TypeinterventionalSponsorUniversity of ValenciaRan2024 to 2028Enrolled56ConditionsBreast Cancer Female, Cardiometabolic Syndrome, Metabolism Disorder, Lipid, Autonomic DysfunctionArmsHIIT program (8 weeks), MPI program (8 weeks)
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Weight change and diabetes risk following breast cancer: a nationwide cohort study.Journal of cancer survivorship : research and practice · 2025
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jordi Monferrer-MarínSport Performance and Physical Fitness Research Group (UIRFIDE; GIUV 2013-140), University of Valencia, Valencia, Spain.ORCID http://orcid.org/0000-0001-9869-5936
Ainoa RoldánSport Performance and Physical Fitness Research Group (UIRFIDE; GIUV 2013-140), University of Valencia, Valencia, Spain.ORCID http://orcid.org/0000-0001-7190-7943
Pablo MonteagudoSport Performance and Physical Fitness Research Group (UIRFIDE; GIUV 2013-140), University of Valencia, Valencia, Spain.ORCID http://orcid.org/0000-0003-4617-8333
Iván Chulvi-MedranoSport Performance and Physical Fitness Research Group (UIRFIDE; GIUV 2013-140), University of Valencia, Valencia, Spain.ORCID http://orcid.org/0000-0002-6612-1759
Cristina Blasco-LafargaSport Performance and Physical Fitness Research Group (UIRFIDE; GIUV 2013-140), University of Valencia, Valencia, Spain. m.cristina.blasco@uv.es.ORCID http://orcid.org/0000-0001-8798-306X

Funding

GESMED Research colaborator (no number)Ministerio de Educación, Cultura y Deporte 21CO1/007096
6 · The paper itself

Abstract

backgroundAgeing affects metabolic flexibility, although physical status could influence this relationship. This cross-sectional study aims to describe and analyse the metabolic flexibility/inflexibility in a group of active older women, together with the impact of ageing and physical status on their oxidation rates and maximal fat oxidation (MFO).

methodsFifteen volunteers (69.00 ± 6.97 years)-from 24 women-completed an incremental cycling test until the second ventilatory threshold. Intensity increased 10 W each 3 min 15 s, starting at 30 W. Gas exchange, heart rate, rate of perceived effort, pain scale and muscle power were registered, together with lactate. VO

resultsFATox was low at MFO (0.13; 95% CI [0.09-0.17] mg/min/kgFFM; 3.50; 95% CI [2.49-4.50] mg/min/kgFFM), with short oxidation-rate curves shifting down and leftward. CHOox and FATox were both low for reduced power with age (77.14 ± 18.58 W and 39.29 ± 9.17 W at P

conclusionsDespite the drop in substrates oxidation with age, physical status (i.e. larger muscular power and energy expenditure) suggests a key role in the preservation of metabolic health with ageing in active women.

Indexed as

CHOoxElderlyEnergy expenditureFATmaxFAToxLactateMetabolic healthMFOMitochondrial dysfunctionMuscular power

Identifiers

PMID35907092
PMCPMC9339052

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.