Evidence map›Paper›PMID 35906999›Full record

ArticleParasitology research2022

First report of rodent-adapted Cryptosporidium wrairi in an immunocompetent child, Spain.

Carolina Hernández-Castro, Alejandro Dashti, Pamela Carolina Köster, Begoña Bailo, Andrea López, María Teresa Llorente, David González-Barrio, Sergio Sánchez, David Carmena

Abstract readCase Reports
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In one paragraph

Article in Parasitology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Rodent-adaptedOne health (Amsterdam, Netherlands) · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carolina Hernández-Castro *Parasitology Reference and Research Laboratory, National Centre for Microbiology, 28220, Majadahonda, Madrid, Spain.ORCID http://orcid.org/0000-0003-0731-6078
Alejandro Dashti *Parasitology Reference and Research Laboratory, National Centre for Microbiology, 28220, Majadahonda, Madrid, Spain.ORCID http://orcid.org/0000-0001-8707-5731
Pamela Carolina KösterParasitology Reference and Research Laboratory, National Centre for Microbiology, 28220, Majadahonda, Madrid, Spain.ORCID http://orcid.org/0000-0001-5963-8824
Begoña BailoParasitology Reference and Research Laboratory, National Centre for Microbiology, 28220, Majadahonda, Madrid, Spain.ORCID http://orcid.org/0000-0002-9453-9431
Andrea LópezFood and Waterborne Bacterial Infections Reference and Research Laboratory, National Centre for Microbiology, 28220, Majadahonda, Madrid, Spain.
María Teresa LlorenteFood and Waterborne Bacterial Infections Reference and Research Laboratory, National Centre for Microbiology, 28220, Majadahonda, Madrid, Spain.
David González-BarrioParasitology Reference and Research Laboratory, National Centre for Microbiology, 28220, Majadahonda, Madrid, Spain.ORCID http://orcid.org/0000-0002-8460-0067
Sergio SánchezFood and Waterborne Bacterial Infections Reference and Research Laboratory, National Centre for Microbiology, 28220, Majadahonda, Madrid, Spain. sergio.sanchez@isciii.es.ORCID http://orcid.org/0000-0001-9903-6203
David CarmenaParasitology Reference and Research Laboratory, National Centre for Microbiology, 28220, Majadahonda, Madrid, Spain. dacarmena@isciii.es.ORCID http://orcid.org/0000-0002-4015-8553

Funding

Instituto de Salud Carlos III PI16CIII/00024Instituto de Salud Carlos III PI18CIII/00043
6 · The paper itself

Abstract

Cryptosporidiosis is a leading cause of childhood diarrhoea. Two species, Cryptosporidium hominis and Cryptosporidium parvum, are responsible for most confirmed cases globally. Close contact with pet animals can be an unnoticed source of children infections. We describe a case of infection by rodent-adapted Cryptosporidium wrairi in a 22-month-old immunocompetent toddler with no clinical manifestations in close contact with a pet guinea pig and poor personal hygiene practices in Majadahonda (Madrid, Spain). Attempts to determine the C. wrairi genotype family at the 60-kDa glycoprotein marker failed repeatedly. This is the first description of C. wrairi in a human host. Although a spurious infection cannot be completely ruled out, data presented here suggest that C. wrairi can be transmitted zoonotically.

Indexed as

CryptosporidiosisCryptosporidiumCryptosporidium parvumAnimalsFecesGenotypeGuinea PigsHumansInfantRodentiaSpainChildrenCryptosporidiosisCryptosporidium wrairiSpainTransmissionZoonosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.