ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging2022
Translingual neural stimulation affects resting-state functional connectivity in mild-moderate traumatic brain injury.
Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Dual Dopaminergic and Limbic-Cognitive Contributions to Gait Parameters in De Novo Parkinson Disease.Neurology · 2026Article
- Gait impairment associated with neuroimaging biomarkers in Alzheimer's disease.Scientific reports · 2025Article
- Translingual neural stimulation induced changes in intra- and inter-network functional connectivity in mild-moderate traumatic brain injury patients.Frontiers in human neuroscience · 2025Article
- Traumatic Brain Injury and Neuromodulation Techniques in Rehabilitation: A Scoping Review.Biomedicines · 2024Article
- Cognitive Functions following Trigeminal Neuromodulation.Biomedicines · 2023Review
- Real world evidence of improved attention and cognition during physical therapy paired with neuromodulation: a brain vital signs study.Frontiers in human neuroscience · 2023Article
- Translingual neural stimulation affects resting-state functional connectivity in mild-moderate traumatic brain injury.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022Article
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
background and purposeTraumatic brain injury (TBI) can lead to movement and balance deficits. In addition to physical therapy, brain-based neurorehabilitation efforts have begun to show promise in improving these deficits. The present study investigated the effectiveness of translingual neural stimulation (TLNS) on patients with mild-to-moderate TBI (mmTBI) and related brain connectivity using a resting-state functional connectivity (RSFC) approach.
methodsResting-state images with 5-min on GE750 3T scanner were acquired from nine participants with mmTBI. Paired t-test was used for calculating changes in RSFC and behavioral scores before and after the TLNS intervention. The balance and movement performances related to mmTBI were evaluated by Sensory Organization Test (SOT) and Dynamic Gait Index (DGI).
resultsCompared to pre-TLNS intervention, significant behavioral changes in SOT and DGI were observed. The analysis revealed increased RSFC between the left postcentral gyrus and left inferior parietal lobule and left Brodmann Area 40, as well as the increased RSFC between the right culmen and right declive, indicating changes due to TLNS treatment. However, there were no correlations between the sensory/somatomotor (or visual or cerebellar) network and SOT/DGI behavioral performance.
conclusionsAlthough the limited sample size may have led to lack of significant correlations with functional assessments, these results provide preliminary evidence that TLNS in conjunction with physical therapy can induce brain plasticity in TBI patients with balance and movement deficits.
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