ArticleEchocardiography (Mount Kisco, N.Y.)2022
The usefulness of speckle tracking echocardiography in identifying subclinical myocardial dysfunction in young adults recovered from mild COVID-19.
Article in Echocardiography (Mount Kisco, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A deeper look at long-term effects of COVID-19 on myocardial function in survivors with no prior heart diseases: a GRADE approach systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Impaired Treg Response and Subclinical Cardiac Dysfunction in Children Following SARS-CoV-2 Infection.The Pediatric infectious disease journal · 2026Article
- Long-term cardiovascular function and cardiopulmonary performance in athletes after COVID-19: results from the COSMO study.Frontiers in cardiovascular medicine · 2026Article
- SPECT Perfusion Defects and Impaired Strain in Mild COVID-19: A Multimodal Imaging Study with a Female-Predominant Cohort.Healthcare (Basel, Switzerland) · 2025Article
- A Comparative Analysis of the Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Infection on the Performance of Clinical Decision-Making Algorithms for Pulmonary Embolism.Journal of clinical medicine · 2024Article
- Cardiac Function and Structure before and after Mild SARS-CoV-2 Infection in Elite Athletes Using Biventricular and Left Atrial Strain.Biomedicines · 2024Article
- Myocardial Work Indices in Patients Recently Recovered from Mild-to-Moderate COVID-19.Journal of clinical medicine · 2024Article
- Multimodality Imaging Evaluation to Detect Subtle Right Ventricular Involvement in Patients with Acute Myocarditis and Preserved Left Ventricular Ejection Fraction.Journal of clinical medicine · 2023Article
- Imaging for Cardiovascular Complications of COVID-19: Cardiac Manifestations in Context.The Canadian journal of cardiology · 2023Review
- Strain Echocardiography in Acute COVID-19 and Post-COVID Syndrome: More than Just a Snapshot.Biomedicines · 2023Review
- Ultrasound during the COVID-19 Pandemic: A Global Approach.Journal of clinical medicine · 2023Review
- Sequence and directivity in cardiac muscle injury of COVID-19 patients: an observational study.Frontiers in cardiovascular medicine · 2023Article
- Pathological Changes in the Lungs of Patients with a Lethal COVID-19 Clinical Course.Diagnostics (Basel, Switzerland) · 2022Article
- The usefulness of speckle tracking echocardiography in identifying subclinical myocardial dysfunction in young adults recovered from mild COVID-19.Echocardiography (Mount Kisco, N.Y.) · 2022Article
- Strengthening Echocardiographic Surveillance for Managing Long-term Cardiac Sequelae of COVID-19 Infection.Journal of cardiovascular echographyArticle
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMyocardial strain assessed with speckle tracking echocardiography is a sensitive marker of cardiac dysfunction. Both left-ventricular global longitudinal strain (LV-GLS) and right ventricular longitudinal strain (RV-LS) were affected by severe SARS-CoV-2 infection. However, data about cardiac involvement in patients with asymptomatic/mild Coronavirus disease-19 (COVID-19) is still lacking.
aimTo evaluate myocardial function using LV-GLS and RV-LS in patients with previous asymptomatic/mild COVID-19.
methodsForty young adults without previously known comorbidities/cardiovascular risk factors and with a confirmed diagnosis of asymptomatic or paucisymptomatic SARS-CoV-2 infection were retrospectively included. A 2D-transthoracic echocardiogram with speckle tracking analysis was performed at least 3 months after the diagnosis. Forty healthy subjects, matched for age, sex, and body surface area in a 1:1 ratio were used as the control group.
resultsLeft ventricular ejection fraction (LVEF), tricuspid annular plane systolic excursion (TAPSE) and RV-LS were comparable between the two groups. LV-GLS was significantly lower in the cases compared to the control group (-22.7 ± 1.6% vs. -25.7 ± 2.3%; p < .001). Moreover, the prevalence of regional peak systolic strain below -16% in at least two segments was three times higher in patients with previous COVID-19 compared to controls (30% vs. 10%, p = .02). In multivariable logistic regression, previous COVID-19 infection was independently associated with reduced LV-GLS values (p < .001).
conclusionSARS-CoV-2 infection may affect left ventricular deformation in 30% of young adult patients despite an asymptomatic or only mildly symptomatic acute illness. Speckle-tracking echocardiography could help early identification of patients with subclinical cardiac involvement, with potential repercussions on risk stratification and management.
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