Evidence map›Paper›PMID 35906702›Full record

ArticleVirology journal2022

Association between common vaginal and HPV infections and results of cytology test in the Zhoupu District, Shanghai City, China, from 2014 to 2019.

Huaping Li, Zhengguang Xiao, Baoling Xing, Suqin Wu, Ying Wang, Zhou Liu, Yanan Zeng, Joseph Cosmas Mushi, Hudie Sun, Ping Li

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Huaping Li *Department of Obstetrics and Gynecology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, No.1500 zhouyuan Road, Pudong New District, Shanghai, 201318, China.
Zhengguang Xiao *Department of Imaging, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, No. 1111 Xianxia Road, Changning District, Shanghai, 200336, China.
Baoling XingDepartment of Obstetrics and Gynecology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, No.1500 zhouyuan Road, Pudong New District, Shanghai, 201318, China.
Suqin WuDepartment of Obstetrics and Gynecology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, No.1500 zhouyuan Road, Pudong New District, Shanghai, 201318, China.
Ying WangDepartment of Obstetrics and Gynecology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, No.1500 zhouyuan Road, Pudong New District, Shanghai, 201318, China.
Zhou LiuDepartment of Obstetrics and Gynecology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, No.1500 zhouyuan Road, Pudong New District, Shanghai, 201318, China.
Yanan ZengCollege of Medical Instrumentation, Shanghai University of Medicine & Health Sciences, No.279 Zhouzhu, Pudong New District, Shanghai, 201318, China.
Joseph Cosmas MushiCollege of Information and Communication Technologies (CoICT), University of Dar Es Salaam, 14113, Dar es Salaam, Tanzania.
Hudie SunSino-European School of Technology, Shanghai University, No.99 Shangda Road, Baoshan District, Shanghai, 200444, China.
Ping LiCollege of Medical Instrumentation, Shanghai University of Medicine & Health Sciences, No.279 Zhouzhu, Pudong New District, Shanghai, 201318, China. lip@sumhs.edu.cn.
Shanghai University of Medicine and Health Sciences · CNShanghai Jiao Tong University · CNShanghai University · CNUniversity of Dar es Salaam · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHPV (human papillomavirus) is an important cause of cervical cancer. Cervical-vaginal infection with pathogens, such as herpes simplex virus (HSV), bacterial vaginosis Trichomonas vaginalis and vaginal candidiasis could be a cofactor. This study aimed to assess the relationship between vaginal infection with HPV genotype and cytology test results and analyze the relationship between vaginal and HPV infections and cervical cancer.

methodsWe performed a district-based study to elucidate the relationship among the vaginal and HPV infections and cervical cancer. We collected the cervical exfoliation data of 23,724 women admitted to the Shanghai Zhoupu Hospital and received ThinPrep cytology test (TCT) and HPV detection between 2014 and 2019.

resultsTotal vaginal infection rate was 5.3%, and the HPV-positive group had a slightly higher vaginal infection rate than the HPV-negative group (P < 0.01). The incidence rate of cervical intraepithelial neoplasia or cervical cancer with vaginal infection was higher than without vaginal infection (P < 0.001).

conclusionHPV/vaginal infection-positive women tended to have abnormal results of TCT. Women with vaginal infection were more likely to develop HPV infection. HSV combined with HPV infection was noted as a causal factor for HSIL.

Indexed as

Papillomavirus InfectionsUterine Cervical DysplasiaUterine Cervical NeoplasmsChinaFemaleHumansPapillomaviridaeVaginal SmearsChinaGenotypeHuman papillomavirusThinPrep cytological testVaginal infection

Identifiers

PMID35906702
PMCPMC9338504
OpenAlexW4288692449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.