ArticleBMC complementary medicine and therapies2022
The effect of hydroalcoholic extract of Psidium guajava L. on experimentally induced oral mucosal wound in rat.
Article in BMC complementary medicine and therapies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 14 citations in OpenAlex.
- Botanical Nanofiber Wound Dressing Loaded withPharmaceutics · 2025Article
- Chitosan Nanoparticles Entrapping AqueousPlants (Basel, Switzerland) · 2025Article
- Bioactive Compounds from Guava Leaves (Molecules (Basel, Switzerland) · 2025Review
- Current and Potential Applications of Monoterpenes and Their Derivatives in Oral Health Care.Molecules (Basel, Switzerland) · 2023Review
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8 authors at 1 institution in 1 country.
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Abstract
backgroundThe aim of this study was to evaluate the biological effects of hydroalcoholic extract of Psidium guajava L leaves and phenytoin as a standard agent on the induced oral mucosal wound.
methodsHundred seventy Sprague Dawley rats were grouped in 5 clusters randomly. Oral mucosal wounds were induced in all rats except for the control group. Phenytoin and guajava leaf extract were used as a mouthwash. Twelve rats from the 5 groups were euthanized on day 7
resultsTotal phenolic content test and DPPH analysis demonstrated the high potential of antioxidant capacity of Psidium guajava L. Decreasing IL-6 and increasing TAC were seen in the guajava hydroalcoholic extract and phenytoin groups. The difference of IL-6 between the wound treated guajava group and the wounded group was significant. The wound treated guajava group and wound treated phenytoin group on the 14
conclusionIn conclusion, hydroalcoholic extract of Psidium guajava L leaves might exert theraputic effects on oral mucositis.
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