Evidence map›Paper›PMID 35906356›Full record

SynthesisInternational journal of colorectal disease2022

Systematic review and meta-analysis of postoperative pain and symptoms control following laser haemorrhoidoplasty versus Milligan-Morgan haemorrhoidectomy for symptomatic haemorrhoids: a new standard.

Varen Zhi Zheng Tan, Ern-Wei Peck, Sharmini S Sivarajah, Winson J Tan, Leonard M L Ho, Jia-Lin Ng, Cheryl Chong, Darius Aw, Franky Mainza, Fung-Joon Foo and 1 more

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in International journal of colorectal disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Varen Zhi Zheng Tan *Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Ern-Wei Peck *Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Sharmini S SivarajahColorectal Service, Division of Surgery, Sengkang General Hospital, SingHealth Services, Singapore, Singapore.
Winson J TanColorectal Service, Division of Surgery, Sengkang General Hospital, SingHealth Services, Singapore, Singapore.
Leonard M L HoColorectal Service, Division of Surgery, Sengkang General Hospital, SingHealth Services, Singapore, Singapore.
Jia-Lin NgColorectal Service, Division of Surgery, Sengkang General Hospital, SingHealth Services, Singapore, Singapore.
Cheryl ChongColorectal Service, Division of Surgery, Sengkang General Hospital, SingHealth Services, Singapore, Singapore.
Darius AwColorectal Service, Division of Surgery, Sengkang General Hospital, SingHealth Services, Singapore, Singapore.
Franky MainzaPondok Indah Hospitals Group, Jakarta, Indonesia.
Fung-Joon FooColorectal Service, Division of Surgery, Sengkang General Hospital, SingHealth Services, Singapore, Singapore.
Frederick H KohColorectal Service, Division of Surgery, Sengkang General Hospital, SingHealth Services, Singapore, Singapore. frederick.koh.h.x@singhealth.com.sg.
Sengkang General Hospital · SGSingHealth · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHaemorrhoidal disease (HD) plagues one in every ten people, with a plethora of surgical treatment modalities, of which laser haemorrhoidoplasty (LHP) is a relatively novel option. This systematic review and meta-analysis objectively evaluated the efficacy, safety, and tolerability of LHP compared against conventional (Milligan-Morgan) open haemorrhoidectomy (CoH).

methodA comprehensive search of MEDLINE, EMBASE, CENTRAL, and Google Scholar was conducted. Randomised controlled trials (RCTs) and comparative cohort studies (CCSs) which compared LHP against CoH were included, with postoperative pain as the primary outcome. Secondary outcomes included intraoperative characteristics, short- and moderate-term outcome, and complications.

resultsA total of 12 studies (6 RCTs and 6 CCSs), with a total of 1824 patients, were analysed. LHP resulted in reduced postoperative pain for the first day (mean difference of 2.07 visual analogue scale units), week, and month. The mean dosage and duration of postoperative analgesia use was similarly lower, with a mean difference of 4.88 mg (morphine) and 2.25 days, respectively. Crucially, recurrence was equivocal (HR: 0.72, CI: 0.21-2.40) at a mean follow-up duration of 8.58 ± 9.55 months. LHP resulted in lower blood loss and was 12.74 min shorter on average. LHP's postoperative recovery time was 9.03 days less with equivalent or decreased risk of most short- and moderate-term complications except anal thrombosis.

conclusionOur study suggests that LHP is more tolerable than CoH, providing patients with superior postoperative quality of life at equivalent moderate-term efficacy. These findings contribute to improved understanding of LHP and its potential at enhancing the quality of HD care.

Indexed as

HemorrhoidectomyHemorrhoidsHumansLasersPain MeasurementPostoperative PainHaemorrhoidsLaserOutcomesSurgeryTechnique

Identifiers

PMID35906356
PMCPMC9388431
OpenAlexW4288702310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.