Evidence map›Paper›PMID 35906239›Full record

ArticleScientific reports2022

Nonlinear functional muscle network based on information theory tracks sensorimotor integration post stroke.

Rory O'Keeffe, Seyed Yahya Shirazi, Seda Bilaloglu, Shayan Jahed, Ramin Bighamian, Preeti Raghavan, S Farokh Atashzar

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rory O'KeeffeDepartment of Electrical and Computer Engineering, New York University, New York, NY, USA.
Seyed Yahya Shirazi *Department of Electrical and Computer Engineering, New York University, New York, NY, USA.
Seda Bilaloglu *Department of Medicine, New York University Langone Health, New York, NY, USA.
Shayan JahedDepartment of Electrical and Computer Engineering, New York University, New York, NY, USA.
Ramin BighamianOffice of Science and Engineering Laboratories, Center for Devices and Radiological Health, United States Food and Drug Administration, Silver Spring, MD, USA.
Preeti RaghavanDepartments of Physical Medicine and Rehabilitation and Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. praghav3@jhmi.edu.
S Farokh AtashzarDepartment of Electrical and Computer Engineering, New York University, New York, NY, USA. f.atashzar@nyu.edu.
New York University · USCenter for Devices and Radiological Health · USJohns Hopkins University · USNYU Langone Health · US

Funding

Strategies for recovery of dexterity post strokeR01HD071978 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RAGHAVAN, PREETI · 2013 to 2017
$3.4M
NICHD NIH HHS R01 HD071978NIH HHS 1R01HD071978
6 · The paper itself

Abstract

Sensory information is critical for motor coordination. However, understanding sensorimotor integration is complicated, especially in individuals with impairment due to injury to the central nervous system. This research presents a novel functional biomarker, based on a nonlinear network graph of muscle connectivity, called InfoMuNet, to quantify the role of sensory information on motor performance. Thirty-two individuals with post-stroke hemiparesis performed a grasp-and-lift task, while their muscle activity from 8 muscles in each arm was measured using surface electromyography. Subjects performed the task with their affected hand before and after sensory exposure to the task performed with the less-affected hand. For the first time, this work shows that InfoMuNet robustly quantifies changes in functional muscle connectivity in the affected hand after exposure to sensory information from the less-affected side. > 90% of the subjects conformed with the improvement resulting from this sensory exposure. InfoMuNet also shows high sensitivity to tactile, kinesthetic, and visual input alterations at the subject level, highlighting its potential use in precision rehabilitation interventions.

Indexed as

StrokeStroke RehabilitationElectromyographyHumansInformation TheoryMusclesUpper Extremity

Identifiers

PMID35906239
PMCPMC9338017
OpenAlexW4288535915

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.