Evidence map›Paper›PMID 35906206›Full record

ArticleNature communications2022

Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides.

Ronja Schiemann, Annika Buhr, Eva Cordes, Stefan Walter, Jürgen J Heinisch, Paola Ferrero, Hendrik Milting, Achim Paululat, Heiko Meyer

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ronja Schiemann *Department of Zoology & Developmental Biology, Osnabrück University, 49076, Osnabrück, Germany.ORCID 0000-0003-2011-2467
Annika Buhr *Department of Zoology & Developmental Biology, Osnabrück University, 49076, Osnabrück, Germany.ORCID 0000-0002-5037-9560
Eva CordesDepartment of Zoology & Developmental Biology, Osnabrück University, 49076, Osnabrück, Germany.
Stefan WalterCenter of Cellular Nanoanalytics Osnabrück - CellNanOs, 49076, Osnabrück, Germany.
Jürgen J HeinischCenter of Cellular Nanoanalytics Osnabrück - CellNanOs, 49076, Osnabrück, Germany.ORCID 0000-0003-4197-4285
Paola FerreroCenter for Cardiovascular Research - CONICET/National University of La Plata, 1900, La Plata, Argentina.ORCID 0000-0002-5582-642X
Hendrik MiltingHeart & Diabetes Center NRW, University of Bochum, Erich & Hanna Klessmann-Institute for Cardiovascular Research and Development, 32545, Bad Oeynhausen, Germany.
Achim PaululatDepartment of Zoology & Developmental Biology, Osnabrück University, 49076, Osnabrück, Germany.ORCID 0000-0002-8845-6859
Heiko MeyerDepartment of Zoology & Developmental Biology, Osnabrück University, 49076, Osnabrück, Germany. Meyer@biologie.uni-osnabrueck.de.ORCID 0000-0002-3304-4523
Osnabrück University · DEConsejo Nacional de Investigaciones Científicas y Técnicas · ARHeart and Diabetes Center North Rhine-Westphalia · DE

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
NIH HHS P40 OD018537
6 · The paper itself

Abstract

Muscle contraction depends on strictly controlled Ca

Indexed as

Calcium-Binding ProteinsNeprilysinCalciumHumansMuscle ContractionMyocardial ContractionMyocytes, CardiacPeptidesSarcoplasmic ReticulumSarcoplasmic Reticulum Calcium-Transporting ATPasesCalciumCalcium-Binding ProteinsNeprilysinPeptidesSarcoplasmic Reticulum Calcium-Transporting ATPases

Identifiers

PMID35906206
PMCPMC9338278
OpenAlexW4288702295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.