Evidence map›Paper›PMID 35906069›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

Multiple Sources of Fast Traveling Waves during Human Seizures: Resolving a Controversy.

Emily D Schlafly, François A Marshall, Edward M Merricks, Uri T Eden, Sydney S Cash, Catherine A Schevon, Mark A Kramer

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Emily D SchlaflyGraduate Program in Neuroscience, Boston University, Boston, Massachusetts 02215.
François A MarshallDepartment of Mathematics and Statistics & Center for Systems Neuroscience, Boston University, Boston, Massachusetts 02215.
Edward M MerricksDepartment of Neurology, Columbia University, New York, New York 10032.ORCID https://orcid.org/0000-0001-8172-3152
Uri T EdenDepartment of Mathematics and Statistics & Center for Systems Neuroscience, Boston University, Boston, Massachusetts 02215.
Sydney S CashDepartment of Neurology, Massachusetts General Hospital & Harvard Medical School, Boston, Massachusetts 02114.ORCID https://orcid.org/0000-0002-4557-6391
Catherine A SchevonDepartment of Neurology, Columbia University, New York, New York 10032.
Mark A KramerDepartment of Mathematics and Statistics & Center for Systems Neuroscience, Boston University, Boston, Massachusetts 02215 mak@bu.edu.

Funding

Seizure localization in humans: the effect of inhibitory surround on the EEGR01NS084142 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SCHEVON, CATHERINE A · 2013 to 2022
$6.0M
Neuroscience Resident Research ProgramUE5NS065743 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI SYDNEY S CASH, Ziv Williams · 2024 to 2026
$2.6M
Understanding the Fast and Slow Spatiotemporal Dynamics of Human SeizuresR01NS110669 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI CASH, SYDNEY S, EDEN, URI TZVI · 2019 to 2023
$2.3M
NINDS NIH HHS R01 NS084142NINDS NIH HHS R01 NS110669NINDS NIH HHS UE5 NS065743
6 · The paper itself

Abstract

During human seizures, organized waves of voltage activity rapidly sweep across the cortex. Two contradictory theories describe the source of these fast traveling waves: either a slowly advancing narrow region of multiunit activity (an ictal wavefront) or a fixed cortical location. Limited observations and different analyses prevent resolution of these incompatible theories. Here we address this disagreement by combining the methods and microelectrode array recordings (

Indexed as

epilepsyhumansictal wavefrontmicroelectrode arraytraveling waves

Identifiers

PMID35906069
PMCPMC9464018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.