Evidence map›Paper›PMID 35905376›Full record

ArticleGut microbes

Samuel D R Dooyema, Jennifer M Noto, Lydia E Wroblewski, M Blanca Piazuelo, Uma Krishna, Giovanni Suarez, Judith Romero-Gallo, Alberto G Delgado, Richard M Peek

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Worldwide research trends on theFrontiers in immunology · 2026
    Pooled it
  2. Review
  3. Review
  4. Mitochondrial Stress inAntioxidants (Basel, Switzerland) · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Gut microbes · 2025
    Article
  9. Article
  10. Biphasic Adaptations of Gastric Epithelial Cells in ChronicInternational journal of molecular sciences · 2025
    Article
  11. Vaccines · 2025
    Review
  12. Article
  13. The STING signaling pathways and bacterial infection.Apoptosis : an international journal on programmed cell death · 2025
    Review
  14. The intersection ofFrontiers in cellular and infection microbiology · 2025
    Review
  15. Dysregulated macrophage immunity inFrontiers in immunology · 2025
    Review
  16. Article
  17. Microbiota and gastric cancer: from molecular mechanisms to therapeutic strategies.Frontiers in cellular and infection microbiology · 2025
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Samuel D R DooyemaDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jennifer M NotoDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Lydia E WroblewskiDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
M Blanca PiazueloDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Uma KrishnaDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Giovanni SuarezDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Judith Romero-GalloDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Alberto G DelgadoDepartment of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Richard M PeekDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Vanderbilt University Medical Center · USVanderbilt University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
Role of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Kevin L Schey · 2009 to 2026
$27.5M
Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
H.Pylori Relationship to Digestive Diseases and CancerR01CA077955 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2003 to 2026
$9.7M
Helicobacter Pylori and Gastrointestinal BiologyR01DK058587 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PEEK, RICHARD M. · 2001 to 2024
$7.8M
Chemical Biology of Infectious Diseases (CBID) Training ProgramT32AI112541 · NIAID · VANDERBILT UNIVERSITY · PI Eric P Skaar · 2015 to 2026
$4.0M
Leica Bond RXS10OD023475 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BOYD, KELLI L. · 2018 to 2018
$213k
NCI NIH HHS P01 CA116087NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA077955NEI NIH HHS P30 EY008126NIAID NIH HHS T32 AI112541NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK058587NIDDK NIH HHS U24 DK059637NIH HHS S10 OD023475
6 · The paper itself

Abstract

Chronic mucosal pathogens have evolved multiple strategies to manipulate the host immune response; consequently, microbes contribute to the development of >2 million cases of cancer/year. Gastric adenocarcinoma is the fourth leading cause of cancer-related death and

Indexed as

Gastrointestinal MicrobiomeHelicobacter InfectionsHelicobacter pyloriNucleic AcidsStomach NeoplasmsAnimalsGastric MucosaImmunity, InnateInflammationMiceNucleic Acidsgastric cancerHelicobacter pyloriinnate immunityRIG-ISTINGTLR9TRIM30

Identifiers

PMID35905376
PMCPMC9341374
OpenAlexW4288696792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.