Evidence map›Paper›PMID 35904725›Full record

SynthesisSpine deformity2022

Systematic review and meta-analysis for the impact of rod materials and sizes in the surgical treatment of adult spine deformity.

Dawn Bowden, Annalisa Michielli, Michelle Merrill, Steven Will

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Spine deformity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Personalized Approaches to Spine Surgery.International journal of spine surgery · 2024
    Article
  5. Article
  6. Article
  7. Rod angulation does not reflect sagittal curvature in adult spinal deformity surgery: comparison of lumbar lordosis and rod contouring.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dawn BowdenDePuy Synthes Spine, Johnson and Johnson Medical Devices, 325 Paramount Drive, Raynham, MA, 02767, USA. dbowden1@ITS.JNJ.com.
Annalisa MichielliDePuy Synthes Spine, Johnson and Johnson Medical Devices, 325 Paramount Drive, Raynham, MA, 02767, USA.
Michelle MerrillDePuy Synthes Spine, Johnson and Johnson Medical Devices, 325 Paramount Drive, Raynham, MA, 02767, USA.
Steven WillDePuy Synthes Spine, Johnson and Johnson Medical Devices, 325 Paramount Drive, Raynham, MA, 02767, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess clinical and safety outcomes associated with different rod materials and diameters in adult spinal deformity (ASD) surgery.

methodsA systematic literature review and meta-analysis evaluated ASD surgery using pedicle screw fixation systems with rods of different materials and sizes. Postoperative outcomes (i.e., Cobb, sagittal vertical axis, and pelvic tilt angle) and complications (i.e., pseudarthrosis and rod breakage) were assessed. Random effects models (REMs) pooled data for outcomes reported in ≥ 2 studies.

resultsAmong 50 studies evaluating ASD surgery using pedicle screw fixation systems, 17 described rod material/diameter. Postoperative outcomes did not statistically differ between cobalt-chromium (CoCr) vs. titanium (Ti) rods (n = 2 studies; mean [95% confidence interval (CI)] sagittal vertical axis angle: CoCr 37.00° [18.58°-55.42°] and Ti 32.58° [24.62°-40.54°]; mean [95% CI] pelvic tilt angle: CoCr 26.20° [22.87°-29.53°] and Ti 20.15° [18.0°-22.31°]). The pooled proportion (95% CI) of pseudarthrosis was 15% (7-22%) for CoCr and 12% (- 8-32%) for stainless steel (SS) (n = 2 studies each; Chi

conclusionsFor ASD patients undergoing posterior fixation and fusion, there are no statistically significant differences in postoperative outcomes or complications among rods of varying materials and diameters. Benchmark postsurgical outcomes and complication rates by rod material and diameter are provided. LEVEL OF EVIDENCE: III.

Indexed as

PseudarthrosisSpinal FusionAdultChromiumChromium AlloysCobaltHumansStainless SteelTitaniumChromiumChromium AlloysCobaltStainless SteelTitaniumAdult spine deformityComplicationsMeta-analysisOutcomesRodsSurgery

Identifiers

PMID35904725
PMCPMC9579115

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.