Evidence map›Paper›PMID 35904450›Full record

ArticleCurrent eye research2022

Neuroanatomy of Adult and Aging Chicken Cornea.

Jiucheng He, Thang Luong Pham, Haydee E P Bazan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current eye research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jiucheng HeNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, USA.
Thang Luong PhamNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, USA.
Haydee E P BazanNeuroscience Center of Excellence, School of Medicine, Louisiana State University Health New Orleans, New Orleans, LA, USA.ORCID 0000-0001-7172-7870
Louisiana State University Health Sciences Center New Orleans · US

Funding

Lipid Mediators in Corneal Nerve RegenerationR01EY019465 · NEI · LSU HEALTH SCIENCES CENTER · PI BAZAN, HAYDEE E.P. · 2009 to 2021
$4.0M
NEI NIH HHS R01 EY019465
6 · The paper itself

Abstract

purposeTo provide a complete nerve architecture and main sensory neuropeptide distribution in the chicken cornea.

methodsAdult chickens aged 6 months and 4 years were used. The whole cornea was stained with protein gene product (PGP) 9.5 antibody-a pan marker for nerve fibers, calcitonin gene-related peptide (CGRP), and substance P (SP) antibodies; whole-mount images were acquired to build an entire view of corneal innervation. Relative corneal epithelial nerve fiber densities, including subbasal bundles and superficial terminals, were assessed by computer-assisted analysis.

resultsAn average of about 76.3 ± 5.7 (

conclusionsThis is the first study to provide a complete map of the entire corneal nerves and CGRP and SP sensory neuropeptide distribution in the adult chicken cornea. The findings show chicken corneal innervation has many differences to human and mammal cornea.

Indexed as

Calcitonin Gene-Related PeptideNeuropeptidesAdultAgingAnimalsChickensCorneaFemaleHumansMaleMammalsNeuroanatomySubstance PCalcitonin Gene-Related PeptideNeuropeptidesSubstance Pagingcalcitonin gene-related peptideChicken corneal innervationsensory nervessubstance P

Identifiers

PMID35904450
PMCPMC9844890
OpenAlexW4288701843

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.