Evidence map›Paper›PMID 35904319›Full record

ReviewJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc2022

Cyclic hematopoiesis in a mixed-breed dog: case report and brief review.

Gary K C Lee, Courtney Barbosa, Gitte Andersen, Christina J Ramirez, Matthew Kornya, Anthony Abrams-Ogg, Katherine Morrison, Gabriella Diamantino, R Darren Wood, Janet Beeler-Marfisi and 3 more

Open access · hybridAbstract readReviewCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Gary K C LeeOntario Veterinary College, University of Guelph, Guelph, ON, Canada.ORCID 0000-0002-1308-8713
Courtney BarbosaPark Animal Hospital, Mississauga, ON, Canada.
Gitte AndersenPark Animal Hospital, Mississauga, ON, Canada.
Christina J RamirezPaw Print Genetics, Neogen, Spokane, WA, USA.
Matthew KornyaOntario Veterinary College, University of Guelph, Guelph, ON, Canada.
Anthony Abrams-OggOntario Veterinary College, University of Guelph, Guelph, ON, Canada.
Katherine MorrisonOntario Veterinary College, University of Guelph, Guelph, ON, Canada.
Gabriella DiamantinoOntario Veterinary College, University of Guelph, Guelph, ON, Canada.
R Darren WoodOntario Veterinary College, University of Guelph, Guelph, ON, Canada.
Janet Beeler-MarfisiOntario Veterinary College, University of Guelph, Guelph, ON, Canada.ORCID 0000-0002-4324-1600
Fernanda AmpueroOntario Veterinary College, University of Guelph, Guelph, ON, Canada.
Laetitia TatierskyOntario Veterinary College, University of Guelph, Guelph, ON, Canada.
Dorothee BienzleOntario Veterinary College, University of Guelph, Guelph, ON, Canada.
University of Guelph · CANeogen (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 8-wk-old, male, mixed-breed puppy was adopted from a rescue organization. From the time of adoption, the puppy suffered episodes of illness affecting various organ systems, which resolved with supportive therapy but relapsed once medical therapy was discontinued. Review of the hematologic data revealed cyclic fluctuations in circulating blood cells. Cyclicity was most prominent in neutrophils, with recurrent severe neutropenia. Neutropenic episodes lasted 5-6 d, with regular cycles of 11-14 d between nadir neutrophil counts. Genetic testing determined that the patient was homozygous mutant for the frameshift mutation in the adaptor protein complex 3 β-subunit (

Indexed as

Dog DiseasesNeutropeniaAdaptor Protein Complex 3AnimalsDogsHematopoiesisMaleAdaptor Protein Complex 3bone marrowcanine diseasescyclic hematopoiesisgenetic diseaseshematologyneutropeniaveterinary pathology

Identifiers

PMID35904319
PMCPMC9597339
OpenAlexW4288714169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.