Evidence map›Paper›PMID 35904285›Full record

ArticleTranscription

A BEN-domain protein and polycomb complex work coordinately to regulate transcription.

Fredy Kurniawan, Supriya G Prasanth

Open access · bronzeAbstract read
In one paragraph

Article in Transcription. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Identification of Novel/RareInternational journal of molecular sciences · 2024
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fredy KurniawanDepartment of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL,USA.
Supriya G PrasanthDepartment of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL,USA.
University of Illinois Urbana-Champaign · US

Funding

Regulation of genomic stability by ORCR01GM125196 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI PRASANTH, SUPRIYA G · 2018 to 2021
$1.3M
NIGMS NIH HHS R01 GM125196
6 · The paper itself

Abstract

Transcription regulation is an important mechanism that controls pluripotency and differentiation. Transcription factors dictate cell fate decisions by functioning cooperatively with chromatin regulators. We have recently demonstrated that BEND3 (BANP, E5R and Nac1 domain) protein regulates the expression of differentiation-associated genes by modulating the chromatin architecture at promoters. We highlight the collaboration of BEND3 with the polycomb repressive complex in coordinating transcription repression and propose a model highlighting the relevance of the BEND3-PRC2 axis in gene regulation and chromatin organization.

Indexed as

Drosophila ProteinsHistonesChromatinDNA, RibosomalMethylationPolycomb-Group ProteinsPolycomb Repressive Complex 2ChromatinDNA, RibosomalDrosophila ProteinsHistonesPolycomb-Group ProteinsPolycomb Repressive Complex 2BEND3differentiationH3K27me3polycomb repressive complextranscription repression

Identifiers

PMID35904285
PMCPMC9467525
OpenAlexW4288714726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.