Evidence map›Paper›PMID 35904230›Full record

ArticleEndocrine connections2022

Sexually dimorphic distribution of kiss1 and kiss2 in the brain of yellowtail clownfish, Amphiprion clarkii.

Yan-Yu Zhang, Xian Zhang, Shao-Yang Bu, Wei-Wei Zhang, Tian-Xiu Li, De-Cai Zheng, Ze-Xiang Huang, Qian Wang

Open access · goldAbstract read
In one paragraph

Article in Endocrine connections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Regulation of theFrontiers in endocrinology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yan-Yu Zhang1Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China.
Xian Zhang1Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China.
Shao-Yang Bu1Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China.
Wei-Wei Zhang1Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China.
Tian-Xiu Li1Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China.
De-Cai Zheng1Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China.
Ze-Xiang Huang1Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China.
Qian Wang1Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China.ORCID 0000-0002-7062-8763
Hainan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kisspeptin system was shown to be a key factor in mediating social stress and reproduction. Yellowtail clownfish, Amphiprion clarkii, is a hermaphrodite fish, whose sex determination and gonadal development are affected by the social status of individuals. The yellowtail clownfish is a fantastic animal model to explore sex determination, but the social status and precise distribution of kiss mRNAs in the brain of this species are unknown. Hererin, a novel in situ hybridization technique, RNAscope, was used to investigate the distribution of kiss1 and kiss2 expressions in the brain of yellowtail clownfish. The coronal planes of brain showed that the kiss1 signal was mainly present in dorsal habenular nucleus (NHd) and kiss2 mRNA was widely expressed in telencephalon, midbrain, and hypothalamus, especially in dorsal part of the nucleus of the lateral recess (NRLd). Additionally, kiss1 and kiss2 signals have sexually dimorphic distribution. The kiss1 mRNA was distributed in NHd, the telencephalon, and lateral part of the diffuse nucleus of the inferior lobe (NDLIl) of females but in NHd and NDLIl of males. kiss2 signals were stronger in females than that in males. The distribution of kiss1 and kiss2 neurons in NHd of habenula and NRLd of hypothalamus may suggest that kiss genes associate environmental signaling and reproductive function in yellowtail clownfish.

Indexed as

kisspeptinRNAscopesexually dimorphic distributionsocial stressyellowtail clownfish

Identifiers

PMID35904230
PMCPMC9346329
OpenAlexW4283641919

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.