Evidence map›Paper›PMID 35904222›Full record

ArticleClinical cardiology2022

Cardiac rehabilitation performance predicts 1-year major adverse cardiovascular events.

Robert Naami, Edmund Naami, Tamer Omari, Sophia Gordon Lowi, Sharon Shalom Natanzon, Vivek Patel, Addee Lerner, Ehud Rozner, Yoav Turgeman, Ofir Koren

Abstract read
In one paragraph

Article in Clinical cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Robert NaamiInternal Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Edmund NaamiSchool of Medicine, University of Illinois, Springfield, Illinois, USA.
Tamer OmariEmek Medical Center, Afula, Israel.
Sophia Gordon LowiEmek Medical Center, Afula, Israel.
Sharon Shalom NatanzonCedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, California, USA.
Vivek PatelCedars-Sinai Medical Center, Smidt Heart Institute, Los Angeles, California, USA.
Addee LernerDavid Geffen School of Medicine, University of California (UCLA), Los Angeles, California, USA.
Ehud RoznerEmek Medical Center, Afula, Israel.
Yoav TurgemanEmek Medical Center, Afula, Israel.
Ofir KorenEmek Medical Center, Afula, Israel.ORCID http://orcid.org/0000-0002-8666-8276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac Rehabilitation is an essential following major adverse cardiovascular events however there is no current data correlating rehab performance to long term outcomes. HYPOTHESIS: Patient exercise performance during cardiac rehabilitation reliably predicts future cardiovascular events.

methodsWe conducted a single-center study of 486 consecutive patients who participated in a CR program between January 2018 and August 2021. We assessed patient performance using a novel index, the CR-score, which integrated duration, speed of work, and workload conducted on each training device (TD). We used a binary recursive partition model to determine the optimal thresholds for cumulative CR score. We used Cox regression analysis to assess the mortality rate among patients who developed MACE ("study group") and those who did not ("control group").

resultsAmong 486 eligible patients, 1-year MACE occurred in 27 (5.5%) patients and was more common in patients with prior cerebrovascular accident or transient ischemic attack (14.8% vs. 3.5%, p < .001). Age, gender, comorbidities, heart failure, and medical treatment did not significantly affect the outcome. The median cumulative CR score of the study group was significantly lower than the control group (595 ± 185.6 vs. 3500 ± 1104.7, p < .0001). A cumulative CR-score of ≥1132 correlated with the outcome (98.5% sensitivity, 99.6% specificity, 95% CI: 0.985-0.997, area 0.994, p < .0001). Patients older than 55 with a cumulative CR score of <1132 were at particularly high risk (OR: 7.4, 95% CI: 2.84-18.42) for 1-year MACE (log-rank p = .03).

conclusionOur proposed CR-score accurately identifies patients at high risk for 1-year MACE following the rehabilitation program. Multicenter validation is required.

Indexed as

Cardiac RehabilitationHeart FailureExerciseExercise TherapyHumansbinary cursive partition modelcardiac rehabilitationcox regression analysisCR-scoredurationMACEoutcomeperformance scorespeed of worktraining deviceworkolad

Identifiers

PMID35904222
PMCPMC9574735

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.